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Tirbanibulin topical Side Effects

Medically reviewed by Last updated on Feb 14, 2024.

Applies to tirbanibulin topical: topical application ointment.

Serious side effects

Along with its needed effects, tirbanibulin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tirbanibulin topical:

More common

Other side effects

Some side effects of tirbanibulin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to tirbanibulin topical: topical ointment.


Very common (10% or more): Adverse reaction related to treatment (16%)[Ref]


Very common (10% or more): Erythema (mild: 22%; moderate: 63%; severe: 6%), flaking/scaling (mid: 26%; moderate: 47%), crusting (mild: 30%; moderate: 14%), swelling (mild: 29%)

Common (1% to 10%): Flaking/scaling (severe: 9%), crusting (severe: 2%), swelling (mild: 9%; severe: <1%), vesiculation/pustulation (mild:7%; moderate to severe: <1%; ), erosion/ulceration (mild: 9%; moderate: 3%), application site pruritus (9%), application site pain (pain, tenderness, stinging, and burning sensation: 10%)[Ref]


1. (2021) "Product Information. Klisyri (tirbanibulin topical)." Almirall

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.