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Tice BCG Vaccine Side Effects

Generic Name: bcg

Note: This page contains side effects data for the generic drug bcg. It is possible that some of the dosage forms included below may not apply to the brand name Tice BCG Vaccine.

For the Consumer

Applies to bcg: intradermal powder for solution

As well as its needed effects, bcg (the active ingredient contained in Tice BCG Vaccine) may cause unwanted side effects that require medical attention.

More common:
  • Accumulation of pus
  • peeling or scaling of the skin
  • sores at place of injection
  • sores at different sites of the skin
  • swollen lymph glands
  • Cough
  • fever
  • increase in bone pain
  • skin rash

For Healthcare Professionals

Applies to bcg: intravesical powder for reconstitution, percutaneous powder for injection


Genitourinary side effects including dysuria (54%), urinary frequency (40%), hematuria (39%), cystitis (29%), urinary tract infection (18%), urgency (18%), genital pain (10%), urinary incontinence (6%), cramps (6%), and contracted bladder (5%) were most commonly reported.[Ref]

Nervous system

Nervous system side effects including malaise (40%) and arthralgia/myalgia (7%) have been reported.[Ref]


Hematologic side effects including anemia (21%), leukopenia (5%), and coagulopathy (3%) have been reported.[Ref]


Gastrointestinal side effects including nausea/vomiting (16%), anorexia (11%), diarrhea (6%), and abdominal pain (3%) have been reported.[Ref]


General side effects including fever (38%), chills (34%), and headache (2%) have been reported.[Ref]


Immunologic side effects including systemic infection (3%) and pulmonary infection (3%) have been reported. Four cases of immune reconstitution syndrome have also been reported.[Ref]


Renal side effects including renal toxicity (10%) have been reported.[Ref]


Dermatologic side effects including skin rash (2%) have been rarely reported.[Ref]


Unclassified cardiovascular side effects were infrequently reported (3%).[Ref]


1. "Product Information. Tice BCG Vaccine (BCG vaccine)." Organon, West Orange, NJ.

2. Puthanakit T, Oberdorfer P, Punjaisee S, Wannarit P, Sirisanthana T, Sirisanthana V "Immune Reconstitution Syndrome Due to Bacillus Calmette-Guerin after Initiation of Antiretroviral Therapy in Children with HIV Infection." Clin Infect Dis 41 (2005): 1049-1052

It is possible that some side effects of Tice BCG Vaccine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

More about Tice BCG Vaccine (bcg)

Consumer resources

Other brands: TheraCys

Professional resources

Other Formulations

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