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Tice BCG Vaccine Side Effects

Generic Name: bcg

Note: This document contains side effect information about bcg. Some of the dosage forms listed on this page may not apply to the brand name Tice BCG Vaccine.

For the Consumer

Applies to bcg: intradermal powder for solution

Other dosage forms:

Along with its needed effects, bcg (the active ingredient contained in Tice BCG Vaccine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

More Common

  • Accumulation of pus
  • peeling or scaling of the skin
  • sores at place of injection
  • sores at different sites of the skin
  • swollen lymph glands


  • Cough
  • fever
  • increase in bone pain
  • skin rash

For Healthcare Professionals

Applies to bcg: intravesical powder for reconstitution, percutaneous powder for injection


Very common (10% or more): Dysuria (60%), increased urgency/frequency (40%), drug induced cystitis (30%), bacterial cystitis (27%), hematuria (27%), pollakiuria

Common (1% to 10%): Urinary tract infection, urinary incontinence, micturition urgency, urine analysis abnormal, bladder cramps, hemorrhage cystitis, urinary retention

Uncommon (0.1% to 1%): Bladder constriction, pyuria, ureteric obstruction

Rare (0.01 to less than 0.1%): Epididymitis

Very rare (less than 0.01%): Orchitis, balanoposthitis, prostatitis, vulvovaginal discomfort[Ref]


Very common (10% or more): Malaise/fatigue/lethargy (19%), fever without infection (13%), influenza-like illness, pyrexia, rigors

Common (1% to 10%): Chills

Very rare (less than 0.01%): Reiter's syndrome, chest pain, peripheral edema, prostate specific antigen increased, weight decreased, BCG osteomyelitis[Ref]

Nervous system

Common (1% to 10%): Dizziness, vertigo

Very rare (less than 0.01%): Dysesthesia, hyperesthesia, paresthesia, somnolence, headache[Ref]


Common (1% to 10%): Anemia, leukopenia

Uncommon (0.1% to 1%): Pancytopenia, thrombocytopenia

Very rare (less than 0.01%): Lymphadenopathy

Frequency not reported: Axillary or cervical lymphadenopathy, regional suppurative lymphadenitis[Ref]


Common (1% to 10%): Abdominal pain, nausea, vomiting, diarrhea

Very rare (less than 0.01%): Dyspepsia, flatulence[Ref]


Common (1% to 10%): Infection

Uncommon (0.1% to 1%): Tuberculosis infections

Very rare (less than 0.01%): Disseminated BCG infection[Ref]


Common (1% to 10%): Skin rash, sweats

Uncommon (0.1% to 1%): Rashes, eruptions and exanthema not otherwise classified

Very rare (less than 0.01%): Lupus vulgaris, alopecia, hyperhidrosis, granuloma[Ref]


Common (1% to 10%): Pneumonitis

Rare (0.01% to 0.1%): Cough

Very rare (less than 0.01%): Pharyngitis, bronchitis, dyspnea, rhinitis[Ref]


Very rare (less than 0.01%): Renal failure acute[Ref]


Common (1% to 10%): Arthralgia, arthritis, myalgia

Very rare (less than 0.01%): Back pain[Ref]


Common (1% to 10%): Allergic symptoms[Ref]


Uncommon (0.1% to 1%): Hepatitis, hepatic enzyme increased[Ref]


Very rare (less than 0.01%): Hypotension[Ref]


Very rare (less than 0.01%): Confusional state[Ref]


Very rare (less than 0.01%): Anorexia[Ref]


Very rare (less than 0.01%): Conjunctivitis[Ref]


Frequency not reported: Injection site reactions: Induration, pustule formation, ulceration, caseous lesions, purulent draining, tenderness, itching, papules[Ref]


1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Tice BCG Vaccine (BCG (BCG vaccine))." Organon, West Orange, NJ.

4. "Product Information. BCG Vaccine (BCG)." Organon Pharmaceuticals, West Orange, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

More about Tice BCG Vaccine (bcg)

Consumer resources

Other brands: TheraCys

Professional resources

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