TDVAX Side Effects
Generic name: diphtheria toxoid/tetanus toxoid
Medically reviewed by Drugs.com. Last updated on Feb 27, 2025.
Note: This document provides detailed information about TDVAX Side Effects associated with diphtheria toxoid/tetanus toxoid. Some dosage forms listed on this page may not apply specifically to the brand name TDVAX.
Applies to diphtheria toxoid/tetanus toxoid: intramuscular suspension.
Precautions
It is very important that you or your child return to your doctor’s office at the right time for the next dose. Be sure to notify your doctor of any unwanted effects that occur after you receive the vaccine.
If you or your child develop a skin rash, hives, or any allergic reaction after receiving this vaccine, tell your doctor right away.
Tell your doctor right away if you or your child are allergic to latex rubber. The prefilled syringes or bottle of vaccine may contain natural rubber latex. This may cause an allergic reaction in patients who are sensitive to latex.
This vaccine will not treat an active infection. If you or your child have an infection due to diphtheria or tetanus, you will need medicine to treat the infection.
Common side effects of TDVAX
Some side effects of diphtheria toxoid/tetanus toxoid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- hard lumps, redness, tenderness, or warmth at the injection site
Less common side effects
Incidence not known
- difficulty with moving
- joint pain
- lack or loss of strength
- muscle aching or cramping
- muscle stiffness
- nausea
- pain in the arms or legs
- swollen joints
- vomiting
Serious side effects of TDVAX
Along with its needed effects, diphtheria toxoid/tetanus toxoid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking diphtheria toxoid/tetanus toxoid:
Less common side effects
- fever
- general feeling of discomfort or illness
- unusual tiredness or weakness
Incidence not known
- bloating or swelling of the face, arms, hands, lower legs, or feet
- burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- chills
- convulsions
- cough
- difficulty with swallowing
- dizziness
- fainting
- fast heartbeat
- hives
- itching
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- rapid weight gain
- shortness of breath
- skin rash
- swelling or puffiness of the face
- swollen, painful, or tender lymph glands in the neck, armpit, or groin
- tightness in the chest
- tingling of the hands or feet
- unusual weight gain or loss
- wheezing
For healthcare professionals
Applies to diphtheria toxoid/tetanus toxoid: intramuscular suspension.
General adverse events
The most common adverse events were slight pain at the injection site, crying, fever, and loss of appetite.[Ref]
Other
- Very common (10% or more): Crying (15.2%)
- Common (1% to 10%): Fever 38C or higher[Ref]
Local
- Very common (10% or more): Slight pain at the injection site (11%)
- Uncommon (0.1% to 1%): Redness/swelling 2.5 cm or larger at the injection site, moderate pain at the injection site, hardness 2.5 cm or larger at the injection site
- Postmarketing reports: Injection site inflammation, injection site hypersensitivity[Ref]
Metabolic
- Common (1% to 10%): Loss of appetite[Ref]
Nervous system
- Frequency not reported: Dizziness
- Postmarketing reports: Convulsion, somnolence, syncope, headache[Ref]
Hematologic
- Postmarketing reports: Lymphadenopathy[Ref]
Cardiovascular
- Postmarketing reports: Pallor[Ref]
Dermatologic
Gastrointestinal
- Postmarketing reports: Nausea[Ref]
See also:
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References
1. (2022) "Product Information. Tetanus-Diphtheria Toxoids, Adult (Td) (tetanus-diphtheria toxoids (Td) adult/adolescent vaccine)." sanofi pasteur
More about TDVAX (diphtheria toxoid/tetanus toxoid)
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Further information
TDVAX side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.