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Tetanus and diphtheria toxoids vaccine (Td)

Generic name: tetanus and diphtheria toxoids vaccine (Td) [ TET-a-nus-and-dif-THEER-ee-a-TOX-oyds-vax-EEN ]
Brand names: TDVAX, Tenivac (Td), Tetanus-Diphtheria Toxoids, Adult (Td), Decavac (Td)
Dosage form: intramuscular suspension (2 units-2 units/0.5 mL; 5 units-2 units/0.5 mL preservative-free)
Drug class: Vaccine combinations

Medically reviewed by Drugs.com on Nov 21, 2024. Written by Cerner Multum.

What is tetanus and diphtheria toxoids vaccine?

Diphtheria and tetanus are serious diseases caused by bacteria.

Diphtheria can cause breathing problems, paralysis, heart failure, or death.

Tetanus (lockjaw) causes painful tightening of the muscles that can lead to "locking" of the jaw so the victim cannot open the mouth, swallow, or breathe. Tetanus can lead to death.

Diphtheria is spread from person to person. Tetanus enters the body through a cut or wound.

The tetanus and diphtheria vaccine (also called Td) is used to help prevent these diseases. This vaccine helps your body develop immunity to the disease, but will not treat an active infection you already have.

Td vaccine is for use in adults and children at least 7 years old.

Like any vaccine, the Td vaccine may not provide protection from disease in every person.

This vaccine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; dizziness, weakness; difficult breathing; swelling of your face, lips, tongue, or throat.

You should not receive a booster vaccine if you had a life threatening allergic reaction after the first shot.

Keep track of all side effects you have. If you receive a booster dose, tell the vaccination provider if the previous shot caused any side effects.

Becoming infected with tetanus or diphtheria is much more dangerous to your health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is low.

Tetanus and diphtheria toxoids vaccine may cause serious side effects. Call your doctor at once if you have:

Common side effects include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

Warnings

Becoming infected with tetanus or diphtheria is much more dangerous to your health than receiving this vaccine.

Before taking this medicine

You should not receive this vaccine if you have ever had a life-threatening allergic reaction to any vaccine that contains diphtheria or tetanus.

This vaccine may need to be postponed or not given at all if you have ever had any of the following reactions after receiving a diphtheria or tetanus vaccine:

Tell your vaccination provider if you have:

You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.

If you are pregnant or breastfeeding, your doctor or vaccination provider should determine whether you need a Td vaccine.

Not approved for use by anyone younger than 7 years old.

How is this vaccine given?

This vaccine is given as an injection (shot) into a muscle.

This vaccine is given to people at least 7 years old, in a series of 3 shots. The first 2 shots are usually given 4 to 8 weeks apart. The booster shot is then given 6 to 12 months after the second shot.

A booster shot is also recommended in children who are 11 or 12 years old, and again every 10 years throughout adulthood.

Your booster schedule may be different from these guidelines. Follow your doctor's instructions or the schedule recommended by your local health department.

If it has been longer than 5 years since your last booster, you may need an emergency booster shot if you have been exposed to tetanus through a skin wound.

Tetanus and diphtheria toxoids vaccine dosing information

Usual Pediatric Dose for Diphtheria Prophylaxis:

0.5 mL intramuscularly in a 5-dose series (at 2, 4, 6, and 15 to 18 months, and at 4 to 6 years)

Comments:
-The first dose may be given at 6 weeks of age.

Use: Active immunization against diphtheria and tetanus in children from 6 weeks to 6 years

Usual Pediatric Dose for Tetanus Prophylaxis:

0.5 mL intramuscularly in a 5-dose series (at 2, 4, 6, and 15 to 18 months, and at 4 to 6 years)

Comments:
-The first dose may be given at 6 weeks of age.

Use: Active immunization against diphtheria and tetanus in children from 6 weeks to 6 years

Daptacel (DTaP), Adacel (Tdap), Boostrix (Tdap), diphtheria toxoid/tetanus toxoid, Pentacel

What happens if I miss a dose?

Contact your vaccination provider if you miss a booster dose or if you get behind schedule. The next dose should be given as soon as possible. There is no need to start over.

Be sure to receive all recommended doses of this vaccine or you may not be fully protected against disease.

What happens if I overdose?

An overdose of this vaccine is unlikely to occur.

What should I avoid before or after receiving this vaccine?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect this vaccine?

Before receiving this vaccine, tell your vaccination provider about all other vaccines you have recently received.

Also tell the vaccination provider if you have recently received drugs or treatments that can weaken the immune system, including:

If you are using any of these medications, you may not be able to receive the vaccine, or may need to wait until the other treatments are finished.

This list is not complete. Other drugs may affect tetanus and diphtheria toxoids vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Does diphtheria toxoid/tetanus toxoid interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.