Sunlenca Side Effects

Generic name: lenacapavir

Medically reviewed by Drugs.com. Last updated on Oct 21, 2023.

Note: This document contains side effect information about lenacapavir. Some dosage forms listed on this page may not apply to the brand name Sunlenca.

Applies to lenacapavir: oral tablet. Other dosage forms:

subcutaneous solution

Serious side effects of Sunlenca

Along with its needed effects, lenacapavir (the active ingredient contained in Sunlenca) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lenacapavir:

Incidence not known

Dark urine
fever
inability to move the arms and legs
joint pain
light-colored stools
muscle tenderness, weakness, or pain
nausea and vomiting
skin rash
sudden numbness and weakness in the arms and legs
unusual tiredness or weakness
upper right abdominal or stomach pain
weight loss
yellow eyes and skin

For Healthcare Professionals

Applies to lenacapavir: oral tablet, subcutaneous solution.

Gastrointestinal

Common (1% to 10%): Nausea^[Ref]

General

The most common adverse reactions reported in at least 3% patients were nausea and injection site reactions.^[Ref]

Hepatic

Common (1% to 10%): Increased alanine aminotransferase (ALT), increased aspartate aminotransferase (AST), increased direct bilirubin^[Ref]

Local

Four percent patients experienced Grade 3 ISRs (erythema, pain, swelling)^[Ref]

Very common (10% or more): Injection site reactions (65%) [include swelling (36%), pain (31%), erythema (31%), nodule (25%), induration (15%), pruritus (6%), extravasation (3%) discomfort (1%), mass (3%), hematoma (1%), edema (1%) and ulcer (1%)]^[Ref]