Solosec Side Effects

Generic name: secnidazole

Medically reviewed by Drugs.com. Last updated on Jun 9, 2024.

Note: This document provides detailed information about Solosec.

Applies to secnidazole: oral granule Side Effects associated with secnidazole. Some dosage forms listed on this page may not apply specifically to the brand name Solosec.

Applies to secnidazole: oral granule.

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

This medicine may cause a vaginal yeast infection. Check with your doctor right away if you have itching of the vagina or genitals or thick, white vaginal discharge with mild or no odor.

If you are taking this medicine for trichomoniasis, your doctor may want to treat your sexual partner at the same time you are being treated, even if he or she has no symptoms. Also, you should avoid having sexual intercourse until treated. These measures will help keep you from getting the infection back again from your partner. If you have any questions about this, talk with your doctor.

This medicine may increase your risk for cancer. Talk to your doctor about this risk.

Serious side effects of Solosec

Along with its needed effects, secnidazole (the active ingredient contained in Solosec) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking secnidazole:

Other side effects of Solosec

Some side effects of secnidazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to secnidazole: oral granule.

Gastrointestinal adverse events

• Common (1% to 10%): Nausea, diarrhea, abdominal pain, vomiting^[Ref]

Nausea, diarrhea, abdominal pain, and vomiting have been reported when this product was taken concomitantly with alcohol.^[Ref]

Genitourinary

• Common (1% to 10%): Vulvovaginal candidiasis, vulvovaginal pruritus^[Ref]

Hepatic

Another nitroimidazole agent structurally related to this drug:

• Postmarketing reports: Severe irreversible hepatotoxicity/acute liver failure in patients with Cockayne syndrome^[Ref]

Cases of severe irreversible hepatotoxicity/acute liver failure, including cases with fatal outcomes with very rapid onset after start of systemic use of metronidazole (another nitroimidazole agent structurally related to this drug), have been reported in patients with Cockayne syndrome; latency from drug start to signs of liver failure has been as short as 2 days.^[Ref]

Nervous system

• Common (1% to 10%): Headache, dysgeusia
• Frequency not reported: Dizziness^[Ref]

Dysgeusia has also been reported during postmarketing experience with this product and other 2 g formulations outside the US.

Dizziness and headache have been reported when this product was taken concomitantly with alcohol.^[Ref]

Respiratory

• Frequency not reported: Productive cough^[Ref]

See also:

Frequently asked questions

• How do you take Solosec?

Further information

Solosec side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer