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Solosec Side Effects

Generic name: secnidazole

Medically reviewed by Last updated on Dec 1, 2020.

Note: This document contains side effect information about secnidazole. Some of the dosage forms listed on this page may not apply to the brand name Solosec.

For the Consumer

Applies to secnidazole: oral granule

Side effects requiring immediate medical attention

Along with its needed effects, secnidazole (the active ingredient contained in Solosec) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking secnidazole:

More common

  • Itching of the vagina or genitals
  • thick, white vaginal discharge with mild or no odor

Less common

  • Pain in the vagina or genital area

Side effects not requiring immediate medical attention

Some side effects of secnidazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to secnidazole: oral granule for reconstitution


Common (1% to 10%): Vulvovaginal candidiasis, vulvovaginal pruritus[Ref]


Nausea, diarrhea, abdominal pain, and vomiting have been reported when this product was taken concomitantly with alcohol.[Ref]

Common (1% to 10%): Nausea, diarrhea, abdominal pain, vomiting[Ref]

Nervous system

Dysgeusia has also been reported during postmarketing experience with this product and other 2 g formulations outside the US.

Dizziness and headache have been reported when this product was taken concomitantly with alcohol.[Ref]

Common (1% to 10%): Headache, dysgeusia

Frequency not reported: Dizziness[Ref]


Frequency not reported: Productive cough

Frequently asked questions


1. "Product Information. Solosec (secnidazole)." Symbiomix Therapeutics , Newark, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.