Sodium Phenylbutyrate / Taurursodiol Side Effects

Medically reviewed by Drugs.com. Last updated on Jan 17, 2024.

Applies to sodium phenylbutyrate / taurursodiol: oral powder for suspension.

Serious side effects

Along with its needed effects, sodium phenylbutyrate/taurursodiol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sodium phenylbutyrate / taurursodiol:

More common side effects

• diarrhea
• nausea
• stomach pain

Other side effects

Some side effects of sodium phenylbutyrate / taurursodiol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• body aches or pain
• chills
• cough
• ear congestion
• fever
• headache
• loss of voice
• sneezing
• sore throat
• stuffy or runny nose
• trouble breathing
• unusual tiredness or weakness

For healthcare professionals

Applies to sodium phenylbutyrate / taurursodiol: oral powder for reconstitution.

General adverse events

The most common adverse reactions were diarrhea, abdominal pain, nausea, and upper respiratory tract infection. While gastrointestinal side effects occurred throughout the study duration, they were more common in the first three weeks of treatment.^[Ref]

Gastrointestinal

• Very common (10% or more): Abdominal pain (21%), diarrhea (25%), nausea (18%), salivary hypersecretion (11%)^[Ref]

Nervous system

• Common (1% to 10%): Dizziness^[Ref]

Other

• Very common (10% or more): Fatigue (12%)^[Ref]

Respiratory

• Very common (10% or more): Upper respiratory tract infection (18%)^[Ref]

Further information

Sodium phenylbutyrate/taurursodiol side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer