Sinecatechins Topical Side Effects

Medically reviewed by Drugs.com. Last updated on Aug 9, 2024.

Applies to sinecatechins topical: topical application ointment.

Precautions

This medicine may make your skin more sensitive to sunlight. Do not expose the area being treated with this medicine to sunlight, sunlamps, or tanning beds .

Avoid having genital, oral, or anal sex while the medicine is on your skin. Make sure you wash the ointment off your skin before you engage in any sexual activity. Also, the medicine contains oils that can weaken latex (rubber) condoms, or diaphragms causing them not to work properly .

Sinecatechins will not keep you from spreading genital warts to other people. Talk with your doctor about safe sex practices .

This medicine is not a cure for genital or anal warts. You may still develop new warts during or after your treatment .

This medicine may stain your clothes and bedding .

Do not use cosmetics or any other skin care products on the same skin area on which you use this medicine, unless directed otherwise by your doctor .

If your condition does not improve within 16 weeks, or if it becomes worse, check with your doctor .

Many patients experience redness, swelling, sores or blisters, burning, or itching after using this medicine. If you experience a severe skin reaction, remove the ointment by washing the area with mild soap and water and contact your doctor right away .

Serious side effects

Along with its needed effects, sinecatechins topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sinecatechins topical:

For healthcare professionals

Applies to sinecatechins topical: topical ointment.

General adverse events

The most frequently reported side effects were local skin and application site reactions, including erythema, pruritus, burning, pain/discomfort, erosion/ulceration, edema, induration, and vesicular rash.

During clinical trials, 5% of patients experienced local adverse events that led to dose reduction, dose interruption, or discontinuation of this drug. These events included application site reactions (local pain, erythema, vesicles, skin erosion/ulceration), phimosis, inguinal lymphadenitis, urethral meatal stenosis, dysuria, genital herpes simplex, vulvitis, hypersensitivity, pruritus, pyodermitis, skin ulcer, erosions in the urethral meatus, and superinfection of warts and ulcers.^[Ref]

Local

• Very common (10% or more): Burning (67%), pain/discomfort (56%), erosion/ulceration (49%), induration (35%)
• Common (1% to 10%): Discharge, bleeding, localized reaction, scar, irritation
• Uncommon (0.1% to 1%): Localized inflammation
• Frequency not reported: Vesicles, necrosis, papules, discoloration, eczema, pigmentation changes, dryness^[Ref]

Dermatologic

• Very common (10% or more): Erythema (70%), pruritus (69%), vesicular rash (20%)
• Common (1% to 10%): Desquamation, rash
• Frequency not reported: Pyodermitis, cutaneous facial rash^[Ref]

Other

• Very common (10% or more): Edema (45%)
• Frequency not reported: Genital herpes simplex, superinfection of warts and ulcers, perianal infection^[Ref]

Hematologic

• Common (1% to 10%): Regional/inguinal lymphadenitis
• Frequency not reported: Staphylococcemia^[Ref]

Genitourinary

• Common (1% to 10%): Phimosis
• Frequency not reported: Dysuria, vulvitis, cervical dysplasia, pelvic pain^[Ref]

Hypersensitivity

• Common (1% to 10%): Type IV hypersensitivity
• Frequency not reported: Hypersensitivity^[Ref]

Nervous system

• Frequency not reported: Hyperesthesia^[Ref]

Renal

• Frequency not reported: Urethral meatal stenosis, erosions in urethral meatus, urethritis^[Ref]

See also:

Further information

Sinecatechins topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer