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Pfizer-BioNTech COVID-19 Vaccine (Do Not Dilute) Side Effects

Generic name: sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine

Note: This document contains side effect information about sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine. Some dosage forms listed on this page may not apply to the brand name Pfizer-BioNTech COVID-19 Vaccine (Do Not Dilute).

Applies to sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine: intramuscular suspension.


Postmarketing reports: Myocarditis, pericarditis[Ref]


Uncommon (0.1% to 1%): Hyperhidrosis

Rare (0.01% to 0.1%): Night sweats

Postmarketing reports: Rash, Angioedema, pruritus, urticaria[Ref]


Very common (10% or more): Diarrhea (up to 10.7%)

Common (1% to 10%): Nausea

Postmarketing reports: Vomiting[Ref]


Uncommon (0.1% to 1%): Lymphadenopathy[Ref]


Postmarketing reports: Severe allergic reactions (including anaphylaxis), other hypersensitivity reactions (e.g., rash, pruritus, urticaria, angioedema)[Ref]


Very common (10% or more): Injection site pain (up to 88.6%), injection site/localized swelling (up to 11.8%), injection site/localized redness (up to 10.4%)[Ref]


Uncommon (0.1% to 1%): Decreased appetite[Ref]


Very common (10% or more): Muscle pain (up to 45.5%), new/worsened muscle pain (up to 39.3%), joint pain (up to 27.5%), new/worsened joint pain (up to 23.8%)

Postmarketing reports: Extremity (arm) pain[Ref]

Nervous system

Very common (10% or more): Headache (up to 64.9%)

Uncommon (0.1% to 1%): Lethargy

Frequency not reported: Bell's palsy, facial paralysis, syncope[Ref]


Very common (10% or more): Fatigue (up to 70.1%), use of antipyretic or pain medication (up to 50.8%), chills (up to 41.5%), fever (up to 17.8%), fever of 38C or higher (up to 16.4%)

Uncommon (0.1% to 1%): Asthenia, malaise[Ref]

More about Pfizer-BioNTech COVID-19 Vaccine (Do Not Dilute) (sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine)


1. Product Information. Pfizer-BioNTech COVID-19 Vaccine PF (SARS-CoV-2 mRNA (tozinameran) vaccine). Pfizer Inc. 2022.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.