Peranex HC Side Effects

Generic name: hydrocortisone / lidocaine topical

Medically reviewed by Drugs.com. Last updated on May 12, 2024.

Note: This document provides detailed information about Peranex HC.

Applies to hydrocortisone/lidocaine topical: cream, gel/jelly Side Effects associated with hydrocortisone / lidocaine topical. Some dosage forms listed on this page may not apply specifically to the brand name Peranex HC.

Applies to hydrocortisone/lidocaine topical: cream, gel/jelly.

Precautions

It is very important that your doctor check your progress at regular visits for any problems or unwanted effects that may be caused by this medicine.

If your symptoms do not improve within a few days or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and for patients who use large amounts for a long time. Talk to your doctor if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

After applying this medicine to the skin of your child, watch the child carefully to make sure that he or she does not get any of the medicine in the eyes or mouth. This medicine can cause serious side effects, especially in children, if it gets into the mouth and is swallowed.

Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Do not use cosmetics or other skin care products on the treated skin areas.

Serious side effects of Peranex HC

Along with its needed effects, hydrocortisone/lidocaine topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydrocortisone / lidocaine topical:

For healthcare professionals

Applies to hydrocortisone / lidocaine topical: rectal cream, rectal cream with applicator, rectal gel with applicator, rectal kit, rectal pad, topical cream, topical kit, topical lotion, topical pad.

Local adverse events

Local side effects have included erythema, edema, transient stinging, burning, transient blanching, and locus of abnormal sensation.

Local side effects associated with topical hydrocortisone have included burning, itching, or irritation, especially if applied to denuded skin or with occlusive dressings. Long-term use of topical corticosteroids may result in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis is occasionally reported.^[Ref]

Endocrine

Endocrine side effects of topical corticosteroids are rare. Glucose intolerance and hyperglycemia may be induced by corticosteroids. These drugs can rarely suppress the hypothalamic-pituitary-adrenal axis. This suppression is more likely when higher potency topical steroids are used over extensive areas and when occlusive dressings are used.^[Ref]

See also:

Further information

Peranex HC side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer