Peranex HC Side Effects
Generic name: hydrocortisone / lidocaine topical
Medically reviewed by Drugs.com. Last updated on Jan 6, 2025.
Note: This document provides detailed information about Peranex HC Side Effects associated with hydrocortisone / lidocaine topical. Some dosage forms listed on this page may not apply specifically to the brand name Peranex HC.
Applies to hydrocortisone/lidocaine topical: cream, gel/jelly.
Serious side effects of Peranex HC
Along with its needed effects, hydrocortisone/lidocaine topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking hydrocortisone / lidocaine topical:
Incidence not known
- burning or stinging sensation of the skin
- paleness or redness of the skin
- swelling of the skin
For healthcare professionals
Applies to hydrocortisone / lidocaine topical: rectal cream, rectal cream with applicator, rectal gel with applicator, rectal kit, rectal pad, topical cream, topical kit, topical lotion, topical pad.
Local adverse events
Local side effects have included erythema, edema, transient stinging, burning, transient blanching, and locus of abnormal sensation.
Local side effects associated with topical hydrocortisone have included burning, itching, or irritation, especially if applied to denuded skin or with occlusive dressings. Long-term use of topical corticosteroids may result in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis is occasionally reported.[Ref]
Endocrine
Endocrine side effects of topical corticosteroids are rare. Glucose intolerance and hyperglycemia may be induced by corticosteroids. These drugs can rarely suppress the hypothalamic-pituitary-adrenal axis. This suppression is more likely when higher potency topical steroids are used over extensive areas and when occlusive dressings are used.[Ref]
References
1. (2004) "Product Information. Lida Mantle HC (hydrocortisone-lidocaine topical)." Bradley Pharmaceuticals Inc
2. (2007) "Product Information. Peranex HC (hydrocortisone-lidocaine topical)." Bradley Pharmaceuticals Inc
More about Peranex HC (hydrocortisone / lidocaine topical)
- Check interactions
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: topical anesthetics
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Further information
Peranex HC side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.