Ontak Side Effects
Generic name: denileukin diftitox
Medically reviewed by Drugs.com. Last updated on Jun 21, 2021.
Note: This document contains side effect information about denileukin diftitox. Some of the dosage forms listed on this page may not apply to the brand name Ontak.
For the Consumer
Applies to denileukin diftitox: parenteral injection concentrate
Side effects include:
Hypoalbuminemia, chills/fever, asthenia, infection, chest pain, hypotension, vasodilation, edema, dyspnea, nausea/vomiting, anorexia, diarrhea, anemia, increase in serum aminotransferase concentrations, dizziness, pain, headache, cough, rash, pruritus.
For Healthcare Professionals
Applies to denileukin diftitox: intravenous solution
Very common (10% or more): Infusion reactions (up to 70.5%), pyrexia (up to 63.6%), rigors (up to 47.3%), fatigue (up to 46.7%), peripheral edema (up to 25.5%), asthenia (up to 18.2%), pain (up to 12.7%), chest pain (up to 12.7%)[Ref]
Very common (10% or more): Capillary leak syndrome (up to 32.5%), hypotension (up to 16.4%)[Ref]
Common (1% to 10%): Visual changes (e.g., visual acuity loss)[Ref]
Very common (10% or more): Rash (up to 24.4%), pruritus (up to 18.2%)[Ref]
Very common (10% or more): Increased ALT or increased AST (up to 84%)[Ref]
Very common (10% or more): Anorexia (up to 20%)[Ref]
Very common (10% or more): Headache (up to 28.9%), dizziness (up to 12.7%), dysgeusia (up to 10.9%)[Ref]
More about Ontak (denileukin diftitox)
Related treatment guides
1. "Product Information. Ontak (denileukin diftitox)." Ligand Pharmaceuticals, San Diego, CA.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.