Ontak Side Effects
Generic Name: denileukin diftitox
Note: This document contains side effect information about denileukin diftitox. Some of the dosage forms listed on this page may not apply to the brand name Ontak.
For the Consumer
Applies to denileukin diftitox: parenteral injection concentrate
Side effects include:
Hypoalbuminemia, chills/fever, asthenia, infection, chest pain, hypotension, vasodilation, edema, dyspnea, nausea/vomiting, anorexia, diarrhea, anemia, increase in serum aminotransferase concentrations, dizziness, pain, headache, cough, rash, pruritus.
For Healthcare Professionals
Applies to denileukin diftitox: intravenous solution
Very common (10% or more): Infusion reactions (up to 70.5%), pyrexia (up to 63.6%), rigors (up to 47.3%), fatigue (up to 46.7%), peripheral edema (up to 25.5%), asthenia (up to 18.2%), pain (up to 12.7%), chest pain (up to 12.7%)[Ref]
Very common (10% or more): Capillary leak syndrome (up to 32.5%), hypotension (up to 16.4%)[Ref]
Common (1% to 10%): Visual changes (e.g., visual acuity loss)[Ref]
Very common (10% or more): Rash (up to 24.4%), pruritus (up to 18.2%)[Ref]
Postmarketing reports: Thyroid conditions (hyperthyroidism, thyroiditis, thyrotoxicosis, and hypothyroidism)
Very common (10% or more): Increased ALT or increased AST (up to 84%)[Ref]
Very common (10% or more): Anorexia (up to 20%)[Ref]
Very common (10% or more): Headache (up to 28.9%), dizziness (up to 12.7%), dysgeusia (up to 10.9%)[Ref]
1. "Product Information. Ontak (denileukin diftitox)." Ligand Pharmaceuticals, San Diego, CA.
Some side effects of Ontak may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Ontak (denileukin diftitox)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- 0 Reviews – Add your own review/rating
- Drug class: miscellaneous antineoplastics
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