Normodyne Side Effects

Generic name: labetalol

Medically reviewed by Drugs.com. Last updated on Feb 10, 2024.

Note: This document provides detailed information about Normodyne Side Effects associated with labetalol. Some dosage forms listed on this page may not apply specifically to the brand name Normodyne.

Applies to labetalol: oral tablet.

Other dosage forms:

• intravenous solution

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects .

Check with your doctor right away if you start having itchy skin, dark urine, loss of appetite, yellow eyes or skin, flu-like symptoms, or stomach pain or tenderness. These could be symptoms of a liver injury .

Labetalol may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing .

This medicine may cause changes in your blood sugar levels. Also, this medicine may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests .

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests .

Common side effects of Normodyne

Some side effects of labetalol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Normodyne

Along with its needed effects, labetalol (the active ingredient contained in Normodyne) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking labetalol:

Get emergency help immediately if any of the following symptoms of overdose occur while taking labetalol:

Symptoms of overdose

• chest pain or discomfort
• lightheadedness, dizziness, or fainting
• slow or irregular heartbeat
• sweating
• unusual tiredness or weakness

For healthcare professionals

Applies to labetalol: compounding powder, intravenous solution, oral tablet.

Cardiovascular adverse events

• Common (1% to 10%): Edema, postural hypotension
• Frequency not reported: Bradycardia, heart block, heart failure, hypotension, ankle edema, increase of an existing intermittent claudication, postural hypotension, cold or cyanotic extremities, Raynaud's phenomenon, paresthesia of the extremities, syncope^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Increased sweating
• Frequency not reported: Systemic lupus erythematosus, rashes (e.g., generalized maculopapular, lichenoid, urticarial, bullous lichen planus, psoriaform, facial erythema, Peyronie's disease, reversible alopecia)^[Ref]

Endocrine

• Frequency not reported: Masking of the normal response to hypoglycemia (sweating and tachycardia); this may be important in some patients with diabetes mellitus^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea, dyspepsia, vomiting
• Uncommon (0.1% to 1%): Diarrhea
• Frequency not reported: Epigastric pain^[Ref]

Genitourinary

• Common (1% to 10%): Ejaculation failure, impotence
• Frequency not reported: Difficulty in micturition (including acute urinary bladder retention)^[Ref]

Hepatic

• Common (1% to 10%): Transient elevations of liver function tests
• Frequency not reported: Hepatic necrosis, hepatitis, cholestatic jaundice^[Ref]

Hypersensitivity

• Rare (less than 0.1%): Hypersensitivity (e.g., rash, urticaria, pruritus, angioedema, dyspnea), anaphylactoid reactions^[Ref]

Immunologic

• Frequency not reported: Antimitochondrial antibodies^[Ref]

Metabolic

• Very rare (less than 0.01%): Hyperkalemia^[Ref]

Musculoskeletal

• Frequency not reported: Muscle cramps, toxic myopathy^[Ref]

Nervous system

• Very common (10% or more): Dizziness (11%)
• Common (1% to 10%): Headache, taste distortion, vertigo, paresthesia, scalp tingling
• Uncommon (0.1% to 1%): Drowsiness
• Frequency not reported: Tremor^[Ref]

Ocular

• Common (1% to 10%): Vision abnormality
• Frequency not reported: Dry eyes
• Postmarketing reports: Intraoperative Floppy Iris Syndrome (IFIS) observed during cataract surgery^[Ref]

Respiratory

• Common (1% to 10%): Nasal stuffiness, dyspnea
• Frequency not reported: Bronchospasm, interstitial lung disease^[Ref]

Other

• Common (1% to 10%): Fatigue, asthenia
• Frequency not reported: Positive antinuclear factor^[Ref]

Psychiatric

• Frequency not reported: Depressed mood and lethargy, hallucinations, psychoses, confusion, sleep disturbances, nightmares^[Ref]

See also:

Further information

Normodyne side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer