Neomycin / polymyxin b / prednisolone ophthalmic Side Effects
Hypersensitivity reactions have occurred due to allergic sensitization.[Ref]
Ocular side effects associated with the corticosteroid component have included elevated intraocular pressure with possible development of glaucoma, optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing. In addition, perforation of the cornea and sclera have occurred when administering topical steroids to patients with diseases that cause thinning of the cornea or sclera.[Ref]
The development of a secondary infection has been reported in patients treated with antimicrobial and corticosteroid combinations. Fungal and viral infections of the cornea can develop with long-term application of corticosteroids.[Ref]
1. "Product Information. Poly-Pred (neomycin/polymyxin B/prednisolone ophthalmic)." Allergan Inc, Irvine, CA.
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