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Neo-Calglucon Side Effects

Generic name: calcium glubionate

Medically reviewed by Last updated on Oct 4, 2022.

Note: This document contains side effect information about calcium glubionate. Some dosage forms listed on this page may not apply to the brand name Neo-Calglucon.

Applies to calcium glubionate: oral syrup.

Serious side effects of Neo-Calglucon

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad constipation.
  • Very upset stomach or throwing up.
  • Feeling confused.

Other side effects of Neo-Calglucon

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Constipation.
  • Upset stomach or throwing up.
  • Stomach pain.
  • Gas.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

For Healthcare Professionals

Applies to calcium glubionate: oral syrup.


When calcium is administered for prolonged periods, hypercalcemia and hypercalciuria may result. This is more likely in patients with hypoparathyroidism who are also receiving large amounts of milk.[Ref]

Metabolic side effects have included hypercalcemia and hypercalciuria.[Ref]


Prolonged administration can result in hypercalciuria and the development of calcium nephrolithiasis in some cases, particularly when in the presence of loop diuretics.[Ref]

Genitourinary side effects have rarely included hypercalciuria and the development of calcium nephrolithiasis.[Ref]


Gastrointestinal side effects have been reported rarely. They have included nausea and constipation.[Ref]


1. "Product Information. Neo-Calglucon (calcium glubionate)." Sandoz Pharmaceuticals Corporation (2001):

2. Fordtran JS "Acid rebound." N Engl J Med 279 (1968): 900-5

3. Edelson GW, Kleerekoper M "Hypercalcemic crisis." Med Clin North Am 79 (1995): 79-92

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.