Naftifine Topical Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 23, 2025.

Applies to naftifine topical: topical cream, topical gel/jelly.

Precautions

It is important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and check you for any problems or unwanted effects that may be caused by this medicine.

If your skin problem does not improve within 4 weeks, or if it becomes worse, check with your doctor.

Check with your doctor right away if you have a skin rash, burning, stinging, swelling, or irritation on the skin.

Do not use this medicine for a skin problem that has not been checked by your doctor.

If you have any questions about this, check with your doctor.

Common side effects of naftifine topical

Some side effects of naftifine topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of naftifine topical

Along with its needed effects, naftifine topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking naftifine topical:

For healthcare professionals

Applies to naftifine topical: topical cream, topical gel.

General adverse events

The most common side effect reported with the 2% cream was pruritus. The most common side effects reported with the 2% gel were application site reactions.^[Ref]

Dermatologic

• Common (1% to 10%): Burning/stinging, dryness, erythema, pruritus/itching
• Uncommon (0.1% to 1%): Rash, skin tenderness
• Postmarketing reports: Redness/irritation, erythema/redness, irritation, burning, blisters, crusting, dryness, mild pruritus/itching, rash^[Ref]

Local

• Common (1% to 10%): Local irritation, application site reactions

Other

• Postmarketing reports: Inflammation, maceration, swelling, serous drainage, pain

Hematologic

• Postmarketing reports: Leukopenia, agranulocytosis

Nervous system

• Postmarketing reports: Headache, dizziness, burning sensation

See also:

Further information

Naftifine topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer