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Mometasone nasal Side Effects

Medically reviewed by Last updated on Oct 12, 2023.

Applies to mometasone nasal: nasal implant, nasal spray.

Serious side effects of Mometasone nasal

Along with its needed effects, mometasone nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mometasone nasal:

More common

  • Bloody mucus or unexplained nosebleeds
  • chills
  • cold
  • cough
  • fever
  • headache
  • hoarseness
  • increased abdominal or stomach pain and cramping during menstrual periods
  • muscle or bone pain
  • stuffy or runny nose

Less common

  • Chest pain
  • discharge or redness in the eye, eyelid, or inner lining of the eyelid
  • earache
  • tightness in the chest
  • troubled breathing


  • Sores inside the nose
  • white patches inside the nose or mouth

Incidence not known

  • Blurred vision
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives, skin rash
  • itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  • unusual tiredness or weakness

Other side effects of Mometasone nasal

Some side effects of mometasone nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Sore throat

Less common

Incidence not known

  • Bad, unusual, or unpleasant (after) taste or smell
  • change in taste or smell

For Healthcare Professionals

Applies to mometasone nasal: nasal implant, nasal spray.


The most commonly reported side effects were headache, viral infection, pharyngitis, epistaxis, and cough.[Ref]

Nervous system

Very common (10% or more): Headache (26%)[Ref]


Frequency not reported: Hypothalamic-pituitary-adrenal (HPA) axis effects including growth reduction[Ref]


Common (1% to 10%): Throat irritation, diarrhea, nausea, abdominal pain, dyspepsia

Frequency not reported: Disturbances of taste and smell[Ref]


Frequency not reported: Hypersensitivity (including anaphylactic reactions, angioedema, bronchospasm, dyspnea)[Ref]


Very common (10% or more): Viral infection (14%)

Frequency not reported: Candida albicans infection, immunosuppression[Ref]


Common (1% to 10%): Earache, otitis media

Frequency not reported: Impaired wound healing[Ref]


Common (1% to 10%): Dysmenorrhea[Ref]


Common (1% to 10%): Musculoskeletal pain, arthralgia, myalgia[Ref]


Common (1% to 10%): Conjunctivitis

Frequency not reported: Glaucoma, increased intraocular pressure, cataract[Ref]


Very common (10% or more): Epistaxis (up to 15%), pharyngitis (12%)

Common (1% to 10%): Upper respiratory tract infection, nasal burning, nasal irritation, nasal ulceration, sneezing, coughing, sinusitis, asthma, bronchitis, influenza-like symptoms, rhinitis

Frequency not reported: Nasal septum perforation[Ref]


Common (1% to 10%): Chest pain[Ref]


1. Product Information. Nasonex (mometasone nasal). Scherer Laboratories Inc.

2. Cerner Multum, Inc. UK Summary of Product Characteristics.

3. Cerner Multum, Inc. Australian Product Information.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.