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Losospan Plus Side Effects

Generic name: magaldrate / simethicone

Note: This document contains side effect information about magaldrate / simethicone. Some dosage forms listed on this page may not apply to the brand name Losospan Plus.

Applies to magaldrate/simethicone: oral suspension, oral tablet chewable.


Musculoskeletal side effects including osteomalacia, bone pain, and muscular weakness have been reported with the use of magaldrate.[Ref]


Other side effects have been reported with the use of magaldrate including malaise, decreased fluoride absorption, milk-alkali syndrome, and aluminum accumulation in serum, bone and the CNS.[Ref]

Nervous system

Nervous system side effects including neurotoxicity and encephalopathy have been reported with the use of magaldrate.[Ref]


Gastrointestinal side effects including rebound hyperacidity, diarrhea, intestinal obstruction, and constipation have been reported with the use of magaldrate.[Ref]


Simethicone has no known side effects.[Ref]

More about Losospan Plus (magaldrate / simethicone)

Related treatment guides


1. Product Information. Ron Acid (magaldrate). Major Pharmaceuticals Inc. 2006.

2. Product Information. Mylicon (simethicone). Johnson and Johnson Medical Inc. 2001;PROD.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.