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Klisyri Side Effects

Generic name: tirbanibulin topical

Medically reviewed by Drugs.com. Last updated on Aug 10, 2022.

Note: This document contains side effect information about tirbanibulin topical. Some dosage forms listed on this page may not apply to the brand name Klisyri.

Applies to tirbanibulin topical: topical application ointment.

Serious side effects of Klisyri

Along with its needed effects, tirbanibulin topical (the active ingredient contained in Klisyri) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tirbanibulin topical:

More common

  • Cracking of the skin
  • crusting of the skin
  • dryness and peeling of the skin
  • flushing, redness of the skin
  • redness, blistering, peeling, or loosening of the skin
  • skin ulcers
  • swelling
  • unusually warm skin

Other side effects of Klisyri

Some side effects of tirbanibulin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Burning, stinging, or pain at the application site
  • itching skin

For Healthcare Professionals

Applies to tirbanibulin topical: topical ointment.

General

Very common (10% or more): Adverse reaction related to treatment (16%)[Ref]

Dermatologic

Very common (10% or more): Erythema (mild: 22%; moderate: 63%; severe: 6%), flaking/scaling (mid: 26%; moderate: 47%), crusting (mild: 30%; moderate: 14%), swelling (mild: 29%)

Common (1% to 10%): Flaking/scaling (severe: 9%), crusting (severe: 2%), swelling (mild: 9%; severe: <1%), vesiculation/pustulation (mild:7%; moderate to severe: <1%; ), erosion/ulceration (mild: 9%; moderate: 3%), application site pruritus (9%), application site pain (pain, tenderness, stinging, and burning sensation: 10%)[Ref]

References

1. "Product Information. Klisyri (tirbanibulin topical)." Almirall (2021):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.