Isosulfan Blue Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 12, 2024.

Applies to isosulfan blue: subcutaneous solution.

Precautions

It is very important that your doctor check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have cold clammy skin; confusion; dizziness; lightheadedness; a skin rash; itching; shortness of breath; sweating; swelling of the face, tongue, and throat; or trouble with breathing after you get the injection.

Make sure your doctor knows if you have had an allergic reaction to any dye or medicine given during a test or procedure.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

This medicine may cause your urine to turn blue for up to 24 hours after you receive this medicine. Talk to your doctor if you have any questions.

Serious side effects of isosulfan blue

Along with its needed effects, isosulfan blue may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking isosulfan blue:

Other side effects of isosulfan blue

Some side effects of isosulfan blue may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to isosulfan blue: injectable solution.

Hypersensitivity adverse events

Hypersensitivity side effects have included life-threatening anaphylactic reactions in up to 2% of patients. Symptoms may include shock, angioedema, urticaria, pruritus, and respiratory distress and occur most often in patients with a personal or family history of bronchial asthma, significant allergies, drug reactions, or previous reactions to triphenylmethane dyes.^[Ref]

The patient should be closely monitored for at least 60 minutes after administration of isosulfan blue. Trained personnel should be available to administer emergency care, including resuscitation.^[Ref]

Dermatologic

Dermatologic side effects have included pruritus, urticaria, angioedema, and transient or long-term blue coloration (tattooing) of the skin.^[Ref]

See also:

Further information

Isosulfan blue side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer