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Hydrocodone HD Side Effects

Generic Name: chlorpheniramine / hydrocodone / phenylephrine

Note: This document contains side effect information about chlorpheniramine / hydrocodone / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Hydrocodone HD.

For the Consumer

Applies to chlorpheniramine / hydrocodone / phenylephrine: oral liquid

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, hydrocodone can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Stop taking this medicine and call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing;

  • a slow heart rate or weak pulse;

  • nervousness, trouble sleeping;

  • severe constipation; or

  • little or no urination.

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Common side effects may include:

  • drowsiness; or

  • feeling restless or excited (especially in children).

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to chlorpheniramine/hydrocodone/phenylephrine: oral liquid, oral syrup

Cardiovascular

Cardiovascular side effects have included hypertension, postural hypotension, tachycardia, and palpitations.[Ref]

Genitourinary

Genitourinary side effects have included ureteral spasm, spasm of vesical sphincters, and urinary retention.[Ref]

Nervous system

Nervous system side effects have included sedation, drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, and dizziness.[Ref]

Psychiatric

Psychiatric side effects have included psychic dependence and mood changes.[Ref]

Ocular

Ocular side effects have included blurred vision.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting.[Ref]

References

1. "Product Information. Tusana-D (chlorpheniramine / hydrocodone / phenylephrine)." Cypress Pharmaceutical Inc, Madison, MS.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

More about Hydrocodone HD (chlorpheniramine / hydrocodone / phenylephrine)

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