Hydrocodone HD Interactions
There are 779 drugs known to interact with Hydrocodone HD (chlorpheniramine / hydrocodone / phenylephrine), along with 24 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 236 are major, 539 are moderate, and 4 are minor.
- View all 779 medications that may interact with Hydrocodone HD
- View Hydrocodone HD alcohol/food interactions (2)
- View Hydrocodone HD disease interactions (24)
Most frequently checked interactions
View interaction reports for Hydrocodone HD (chlorpheniramine / hydrocodone / phenylephrine) and the medicines listed below.
- alprazolam
- amlodipine
- atorvastatin
- clonazepam
- Crestor (rosuvastatin)
- cyclobenzaprine
- Cymbalta (duloxetine)
- gabapentin
- hydrochlorothiazide
- hydrocodone
- hydroxyzine
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- meloxicam
- metformin
- methocarbamol
- Metoprolol Tartrate (metoprolol)
- Nexium (esomeprazole)
- omeprazole
- pantoprazole
- prednisone
- simvastatin
- Synthroid (levothyroxine)
- tizanidine
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- zolpidem
Hydrocodone HD alcohol/food interactions
There are 2 alcohol/food interactions with Hydrocodone HD (chlorpheniramine / hydrocodone / phenylephrine).
Hydrocodone HD disease interactions
There are 24 disease interactions with Hydrocodone HD (chlorpheniramine / hydrocodone / phenylephrine) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- BPH
- diabetes
- glaucoma
Report options
More about Hydrocodone HD (chlorpheniramine / hydrocodone / phenylephrine)
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.