Skip to Content

Hexabrix Side Effects

Generic name: ioxaglate

Note: This document contains side effect information about ioxaglate. Some of the dosage forms listed on this page may not apply to the brand name Hexabrix.

Applies to ioxaglate: injectable solution

General

The most frequent adverse reactions are nausea, vomiting, facial flush and a feeling of body warmth. These reactions are usually of brief duration. In clinical trials, this drug produced less discomfort (pain and heat) up on injection than other contrast agents.[Ref]

Cardiovascular

Common (1% to 10%): Facial flushing

Uncommon (0.1% to 1%): Thrombosis

Rare (0.01% to 0.1%): Thrombophlebitis; severe cases of hypotensive shock, coronary insufficiency, cardiac arrhythmia, fibrillation and arrest

Very rare (less than 0.01%): Disseminated intravascular coagulation

Frequency not reported: Generalized vasodilation, flushing, venospasm. Vascular constriction due to injection rate. Cardiac decompensation, serious arrhythmias, myocardial ischemia or infarction may occur during coronary arteriography and left ventriculography.[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, vomiting[Ref]

Endocrine

Uncommon (0.1% to 1%): Thyroid function tests indicative of hypothyroidism or transient thyroid suppression in adults and pediatric patients (including infants)[Ref]

Dermatologic

Frequency not reported: Extravasation with burning pain, hematomas, ecchymosis, tissue necrosis[Ref]

Hypersensitivity

Frequency not reported: Dermal manifestations (urticaria with or without pruritus, erythema, maculopapular rash); dry mouth, sweating, conjunctival symptoms; facial, peripheral, and angioneurotic edema; symptoms related to the respiratory system include sneezing, nasal stuffiness, coughing, choking, dyspnea, chest tightness and wheezing, which may be initial manifestations of more severe and infrequent reactions including asthmatic attack, laryngospasm and bronchospasm with or without edema, pulmonary edema, apnea and cyanosis[Ref]

Nervous system

Frequency not reported: Headache, trembling, shaking, lightheadedness, spasm, convulsions, aphasia, syncope, paresis, paralysis resulting from spinal cord injury and pathology associated with the syndrome of transverse myelitis, visual field losses which are usually transient but may be permanent, coma, death[Ref]

Other

Frequency not reported: Chills without fever, hyperthermia[Ref]

Renal

Frequency not reported: Temporary renal shutdown or other nephropathy[Ref]

Medically reviewed by Drugs.com. Last updated on Feb 9, 2021.

More about Hexabrix (ioxaglate)

Consumer resources

Professional resources

References

1. "Product Information. Hexabrix 200 (ioxaglate)." Tyco Healthcare Group Canada Inc, Quebec City, IN.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.