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Hexabrix

Generic Name: Ioxaglate Meglumine and Ioxaglate Sodium (eye ox AG late MEG loo meen & eye ox AG late SOW dee um)
Brand Name: Hexabrix

Medically reviewed on Sep 5, 2018

Warning

  • This medicine must not be given into the spine.
  • Very bad health problems, paralysis, and death have happened when contrast has been given into blood vessels in the spinal cord. Talk with the doctor.
  • This medicine is given as a shot into a vein or artery only.

Uses of Hexabrix:

  • It is used before an x-ray or an alike test.

What do I need to tell my doctor BEFORE I take Hexabrix?

For all uses of Hexabrix (ioxaglate meglumine and ioxaglate sodium):

  • If you have an allergy to ioxaglate meglumine, ioxaglate sodium, or any other part of Hexabrix (ioxaglate meglumine and ioxaglate sodium).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are dehydrated, have been eating poorly, or have used a laxative or water pill before Hexabrix (ioxaglate meglumine and ioxaglate sodium).
  • If you have had a skin reaction to Hexabrix (ioxaglate meglumine and ioxaglate sodium) or another drug like it in the past.
  • If you are taking metformin, talk with doctor.
  • If you are breast-feeding. Do not breast-feed for 24 hours after getting Hexabrix (ioxaglate meglumine and ioxaglate sodium).

If used before an x-ray of the uterus and fallopian tubes:

  • If you are having your menstrual period or you have a genital infection.
  • If you have had a type of tissue taken out (curettage) or a type of cervix biopsy (conization) within the past 30 days.
  • If you are pregnant or may be pregnant. Do not take Hexabrix (ioxaglate meglumine and ioxaglate sodium) if you are pregnant.

If used before an x-ray of a joint:

  • If you have an infection in or near the joint being x-rayed.

This is not a list of all drugs or health problems that interact with Hexabrix (ioxaglate meglumine and ioxaglate sodium).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Hexabrix (ioxaglate meglumine and ioxaglate sodium) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Hexabrix?

  • Tell all of your health care providers that you take Hexabrix (ioxaglate meglumine and ioxaglate sodium). This includes your doctors, nurses, pharmacists, and dentists.
  • Very bad and sometimes deadly allergic side effects have rarely happened. Talk with your doctor.
  • Health problems like blood clots have happened with Hexabrix (ioxaglate meglumine and ioxaglate sodium) when used with some procedures. Sometimes, blood clots may cause heart attack and stroke, which may be deadly. If you have questions, talk with the doctor.
  • Seizures and death have happened when contrast has been given to people with bleeding in the brain. Talk with the doctor.
  • Very bad kidney problems and sometimes death have happened when contrast has been given to people with multiple myeloma. Talk with the doctor.
  • Thyroid problems have happened after use of Hexabrix (ioxaglate meglumine and ioxaglate sodium). Some people had to be treated for these thyroid problems. Talk with the doctor.
  • A very bad and sometimes deadly reaction has happened with Hexabrix (ioxaglate meglumine and ioxaglate sodium). Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. Talk with the doctor.
  • If you have sickle cell disease, talk with your doctor.
  • This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Hexabrix (ioxaglate meglumine and ioxaglate sodium).
  • If you are 65 or older, use Hexabrix (ioxaglate meglumine and ioxaglate sodium) with care. You could have more side effects.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Hexabrix (ioxaglate meglumine and ioxaglate sodium) while you are pregnant.

How is this medicine (Hexabrix) best taken?

Use Hexabrix (ioxaglate meglumine and ioxaglate sodium) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • This medicine is given as a shot into a vein or artery only.
  • Other drugs may be given before Hexabrix (ioxaglate meglumine and ioxaglate sodium) to help avoid side effects.
  • You will need to be sure that you are not dehydrated before getting Hexabrix (ioxaglate meglumine and ioxaglate sodium). Check with your doctor to see if you need to drink extra fluids before getting Hexabrix (ioxaglate meglumine and ioxaglate sodium).
  • Drink lots of noncaffeine liquids after using Hexabrix (ioxaglate meglumine and ioxaglate sodium) unless told to drink less liquid by your doctor.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Sneezing.
  • Stuffy nose.
  • Cough.
  • Choking.
  • Shortness of breath.
  • Blue or gray skin color.
  • Chest pain or pressure or a fast heartbeat.
  • A heartbeat that does not feel normal.
  • Very bad dizziness or passing out.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • Seizures.
  • This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
  • Very bad skin reactions (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen from 1 hour to several weeks after getting this drug. These skin reactions can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.

What are some other side effects of Hexabrix?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Flushing.
  • Feeling of warmth.
  • Upset stomach or throwing up.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Hexabrix?

  • If you need to store Hexabrix (ioxaglate meglumine and ioxaglate sodium) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Hexabrix (ioxaglate meglumine and ioxaglate sodium), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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