Glucarpidase Side Effects
Medically reviewed by Drugs.com. Last updated on Sep 3, 2020.
For the Consumer
Applies to glucarpidase: intravenous powder for solution
Side effects requiring immediate medical attention
Along with its needed effects, glucarpidase may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking glucarpidase:
- Blurred vision
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness
- difficulty with swallowing
- joint pain, stiffness, or swelling
- pounding in the ears
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the skin
- shortness of breath
- slow or fast heartbeat
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- troubled breathing or swallowing
Side effects not requiring immediate medical attention
Some side effects of glucarpidase may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- feeling of warmth
- redness of the face, neck, arms, and occasionally, upper chest
- shakiness in the legs, arms, hands, or feet
- sore throat
- trembling or shaking of the hands or feet
For Healthcare Professionals
Applies to glucarpidase: intravenous powder for injection
Very common (10% or more): Anti-glucarpidase antibodies (21%)[Ref]
Uncommon (0.1% to 1%): Hypersensitivity (including anaphylactic reactions)[Ref]
Common (1% to 10%): Flushing, hypotension
Uncommon (0.1% to 1%): Hypertension[Ref]
Uncommon (0.1% to 1%): Rash[Ref]
Common (1% to 10%): Nausea, vomiting
Uncommon (0.1% to 1%): Diarrhea[Ref]
Common (1% to 10%): Paresthesia, headache, burning sensation
Uncommon (0.1% to 1%): Tremor[Ref]
Uncommon (0.1% to 1%): Blurred vision[Ref]
Common (1% to 10%): Feeling hot[Ref]
Uncommon (0.1% to 1%): Throat irritation, throat tightness[Ref]
1. "Product Information. Voraxaze (glucarpidase)." BTG International Inc, West Conshohocken, PA.
More about glucarpidase
- Other brands
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.