FUDR Side Effects

Generic name: floxuridine

Medically reviewed by Drugs.com. Last updated on Dec 20, 2024.

Note: This document provides detailed information about FUDR Side Effects associated with floxuridine. Some dosage forms listed on this page may not apply specifically to the brand name FUDR.

Applies to floxuridine: injection powder for solution.

Serious side effects of FUDR

Along with its needed effects, floxuridine (the active ingredient contained in FUDR) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.

Check with your doctor immediately if any of the following side effects occur while taking floxuridine:

Other side effects of FUDR

Some side effects of floxuridine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

This medicine sometimes causes temporary thinning of hair. After treatment with floxuridine has ended, normal hair growth should return.

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.

While you are being treated with floxuridine, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Floxuridine may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid persons who have recently taken oral polio vaccine. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

For healthcare professionals

Applies to floxuridine: injectable powder for injection.

Other adverse events

• Frequency not reported: Fever, lethargy, malaise, weakness

Adverse reactions to the arterial infusion of this drug are generally related to the procedural complications of regional arterial infusion. The complications include arterial aneurysm, arterial ischemia, arterial thrombosis, embolism, fibromyositis, thrombophlebitis, hepatic necrosis, abscesses, infection at the catheter site, bleeding at the catheter site and/or a blocked, leaking, or displaced catheter.

Laboratory abnormalities include BSP, prothrombin, total proteins, sedimentation rate and thrombocytopenia.^[Ref]

Gastrointestinal

• Frequency not reported: Stomatitis, esophagopharyngitis (at the first visible sign), nausea, vomiting, diarrhea, enteritis, stomatitis, duodenal ulcer, duodenitis, gastritis, bleeding, gastroenteritis, glossitis, pharyngitis, anorexia, cramps, abdominal pain, possible intra- and extrahepatic biliary sclerosis, acalculous cholecystitis^[Ref]

Hematologic

• Frequency not reported: Leukopenia (WBC under 3500) or a rapidly falling white blood count, anemia, leukopenia, thrombocytopenia, hemorrhage (from any site)^[Ref]

Hepatic

• Frequency not reported: Elevations of alkaline phosphatase, serum transaminase, serum bilirubin, and lactic dehydrogenase^[Ref]

Dermatologic

• Frequency not reported: Alopecia, dermatitis, nonspecific skin toxicity, rash^[Ref]

Cardiovascular

• Frequency not reported: Myocardial ischemia^[Ref]

Nervous system

• Frequency not reported: Neurotoxicity

See also:

Further information

FUDR side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer