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Folacin-800 Side Effects

Generic Name: folic acid

Note: This page contains information about the side effects of folic acid. Some of the dosage forms included on this document may not apply to the brand name Folacin-800.

For the Consumer

Applies to folic acid: capsule, injectable, solution, tablet

In addition to its needed effects, some unwanted effects may be caused by folic acid (the active ingredient contained in Folacin-800). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking folic acid, check with your doctor or nurse as soon as possible:

Rare
  • Fever
  • general weakness or discomfort
  • reddened skin
  • shortness of breath
  • skin rash or itching
  • tightness in chest
  • troubled breathing
  • wheezing

For Healthcare Professionals

Applies to folic acid: compounding powder, injectable solution, oral tablet

Gastrointestinal

Rare (less than 0.1%): Mild gastrointestinal upset, nausea, abdominal distension, flatulence[Ref]

Nausea, abdominal distension, and flatulence were reported in patients taking 15 mg folic acid daily for 1 month.[Ref]

Nervous system

Bitter or bad taste, altered sleep patterns, difficulty concentrating, overactivity, and impaired judgement were reported in patients taking 15 mg folic acid (the active ingredient contained in Folacin-800) daily for 1 month.
Increased seizure incidence was seen in some epileptic patients receiving phenobarbital, primidone, or diphenylhydantoin.[Ref]

Frequency not reported: Bitter or bad taste, altered sleep patterns, difficulty concentrating, overactivity, impaired judgement, increased incidence of seizures in some epileptic patients[Ref]

Hypersensitivity

Rare (less than 0.1%): Allergic responses (including erythema, skin rash, itching, general malaise, respiratory difficulty due to bronchospasm), anaphylaxis (including shock)[Ref]

Metabolic

Rare (less than 0.1%): Anorexia
Frequency not reported: Decreased vitamin B12 serum levels, worsening symptoms of B12 deficiency[Ref]

Anorexia was reported in patients taking 15 mg folic acid daily for 1 month.
Decreased vitamin B12 serum levels was reported with prolonged folic acid therapy.[Ref]

Other

Frequency not reported: Decreased diphenylhydantoin serum levels[Ref]

Decreased diphenylhydantoin serum levels were reported in patients taking 5 or 15 mg folic acid daily.[Ref]

Psychiatric

Irritability, excitement, mental depression, and confusion were reported in patients taking 15 mg folic acid (the active ingredient contained in Folacin-800) daily for 1 month.[Ref]

Frequency not reported: Irritability, excitement, mental depression, confusion[Ref]

References

1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Folic Acid (folic acid)." Method Pharmaceuticals, LLC, Arlington, TX.

Not all side effects for Folacin-800 may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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