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Eulexin Side Effects

Generic name: flutamide

Medically reviewed by Drugs.com. Last updated on Jun 21, 2024.

Note: This document provides detailed information about Eulexin Side Effects associated with flutamide. Some dosage forms listed on this page may not apply specifically to the brand name Eulexin.

Applies to flutamide: oral capsule.

Important warnings This medicine can cause some serious health issues

Oral route (capsule)

Liver failure has been reported in patients taking flutamide.

Evidence of hepatic injury occurred usually within the first 3 months and included elevated serum transaminase levels, jaundice, hepatic encephalopathy, and death related to acute hepatic failure.

Serum transaminase levels should be measured prior to starting treatment, monthly for the first 4 months of therapy, and periodically thereafter.

Flutamide is not recommended in patients whose ALT values exceed twice the upper limit of normal and should be discontinued if the ALT rises above 2 times the upper limit of normal or jaundice occurs during therapy.

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: clay-colored stools; dark urine; fever; headache; loss of appetite; nausea and vomiting; pain or tenderness in the upper right side of the stomach; unusual tiredness or weakness; or yellow eyes or skin.

This medicine may cause gynecomastia (swelling of the breasts and breast soreness) in some patients. If you have questions on this, ask your doctor.

Do not take other medicines unless they have been discussed with your doctor. Your doctor may adjust the doses of your medications or monitor you carefully for side effects.

Serious side effects of Eulexin

Along with its needed effects, flutamide (the active ingredient contained in Eulexin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking flutamide:

More common side effects

  • black, tarry stools
  • bloody or cloudy urine
  • continuing diarrhea
  • continuing stomach pain
  • difficult, burning, or painful urination
  • frequent urge to urinate
  • pale skin
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Less common side effects

  • blurred vision
  • chest pain
  • chills
  • cough
  • difficulty with breathing
  • dizziness
  • drowsiness
  • fever
  • headache
  • nervousness
  • pounding in the ears
  • shortness of breath
  • slow or fast heartbeat
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling
  • swollen glands

Rare side effects

  • abdominal or stomach pain
  • clay-colored stools
  • dark urine
  • general tiredness and weakness
  • itching
  • light-colored stools
  • loss of appetite
  • nausea and vomiting
  • rash
  • tumor
  • unpleasant breath odor
  • upper right abdominal pain
  • vomiting of blood
  • yellow eyes and skin

Incidence not known

  • back, leg, or stomach pains
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • bluish-colored lips, fingernails, or palms
  • discoloration of the urine
  • dizziness or lightheadedness
  • flushing or redness of the skin
  • general body swelling
  • headache
  • itching
  • joint or muscle pain
  • nosebleeds
  • rapid heart rate
  • red irritated eyes
  • red skin lesions, often with a purple center
  • unusually warm skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking flutamide:

Symptoms of overdose

Other side effects of Eulexin

Some side effects of flutamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • decreased interest in sexual intercourse
  • diarrhea
  • feeling of warmth
  • inability to have or keep an erection
  • indigestion
  • loss in sexual ability, desire, drive, or performance
  • passing of gas
  • redness of the face, neck, arms and occasionally, upper chest
  • stomach pain, fullness, or discomfort
  • sudden sweating
  • swelling of the breasts or breast soreness in both females and males

Less common side effects

  • depression
  • drowsiness
  • fear or nervousness
  • mood or mental changes

For healthcare professionals

Applies to flutamide: oral capsule.

Hepatic adverse events

Hematologic

Nervous system

Cardiovascular

Dermatologic

Endocrine

Gastrointestinal

Musculoskeletal

Psychiatric

Genitourinary

Respiratory

Immunologic

Ocular

Metabolic

Oncologic

See also:

References

1. (2002) "Product Information. Eulexin (flutamide)." Schering Corporation

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Frequently asked questions

Further information

Eulexin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.