Endal HD Side Effects

Generic Name: diphenhydramine / hydrocodone / phenylephrine

Note: This document contains side effect information about diphenhydramine / hydrocodone / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Endal HD.

For the Consumer

Applies to diphenhydramine / hydrocodone / phenylephrine: oral suspension extended release, oral syrup

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• pounding heartbeats or fluttering in your chest;

• a light-headed feeling, like you might pass out;

• severe anxiety, confusion, fear;

• painful or difficult urination;

• little or no urinating; or

• dangerously high blood pressure (severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats).

Common side effects may include:

• dizziness, drowsiness;

• mood changes;

• blurred vision; or

• nausea, vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to diphenhydramine / hydrocodone / phenylephrine: oral suspension extended release, oral syrup

Nervous system

Nervous system side effects have included lightheadedness, nervousness, dizziness, drowsiness, sedation, mental clouding, headache, insomnia, tremors, weakness, lethargy, hallucinations, convulsions, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, itchy and prickly sensations, and mood changes.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included difficulty swallowing, dry mouth, anorexia, nausea, vomiting, and heartburn.^[Ref]

Genitourinary

Genitourinary side effects have included ureteral spasm, spasm of vesicle sphincters, urinary retention, and dysuria.^[Ref]

Cardiovascular

Cardiovascular side effects have included pallor, tachycardia, palpitations, irregular heart beat, arrhythmias and cardiovascular collapse with hypotension.^[Ref]

Respiratory

Respiratory side effects have included respiratory difficulty and shortness of breath.^[Ref]

Ocular

Ocular side effects have included blurring of vision.^[Ref]

Dermatologic

Dermatologic side effects have included rare reports of dermatitis.^[Ref]

Some side effects of Endal HD may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.