Endal-HD Plus Side Effects

Generic name: chlorpheniramine / hydrocodone / phenylephrine

Note: This document provides detailed information about Endal-HD Plus Side Effects associated with chlorpheniramine / hydrocodone / phenylephrine. Some dosage forms listed on this page may not apply specifically to the brand name Endal-HD Plus.

Applies to chlorpheniramine/hydrocodone/phenylephrine: oral liquid, oral syrup.

Important warnings This medicine can cause some serious health issues

Hydrocodone can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

This medicine is not for use in anyone under 18.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, hydrocodone can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Stop taking this medicine and call your doctor at once if you have:

• noisy breathing, sighing, shallow breathing;

• a slow heart rate or weak pulse;

• nervousness, trouble sleeping;

• severe constipation; or

• little or no urination.

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Common side effects may include:

• drowsiness; or

• feeling restless or excited (especially in children).

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to chlorpheniramine/hydrocodone/phenylephrine: oral liquid, oral syrup.

Cardiovascular adverse events

Cardiovascular side effects have included hypertension, postural hypotension, tachycardia, and palpitations.^[Ref]

Genitourinary

Genitourinary side effects have included ureteral spasm, spasm of vesical sphincters, and urinary retention.^[Ref]

Nervous system

Nervous system side effects have included sedation, drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, and dizziness.^[Ref]

Psychiatric

Psychiatric side effects have included psychic dependence and mood changes.^[Ref]

Ocular

Ocular side effects have included blurred vision.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea and vomiting.^[Ref]

Further information

Endal-HD Plus side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer