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Endal CD (old formulation) Side Effects

Generic Name: codeine / diphenhydramine / phenylephrine

Note: This document contains side effect information about codeine / diphenhydramine / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Endal CD (old formulation).

Applies to codeine/diphenhydramine/phenylephrine: oral syrup

Nervous system

Nervous system side effects have included drowsiness, dizziness, headache, nervousness, restlessness, impairment of mental performance, weakness, mental clouding, lethargy, anxiety, convulsions, CNS depression, tremor, and insomnia.[Ref]


Psychiatric side effects have included fear, dysphoria, psychic dependence, feeling of well-being, confusion, and mood changes.[Ref]


Cardiovascular side effects have included tachycardia, palpitations, arrhythmias, change in heart rate, and cardiovascular collapse with hypotension.[Ref]


Gastrointestinal side effects have included loss of appetite, nausea, constipation, dry mouth, anorexia, vomiting, and heartburn.[Ref]


Genitourinary side effects have included dysuria, polyuria, ureteral spasm, spasm of vesical sphincters, urinary disturbances, and urinary retention.[Ref]


Respiratory side effects have included respiratory difficulty and respiratory depression.[Ref]


Dermatologic side effects have included increased sweating, pallor, skin hash, hives, swelling of face, and dermatitis.[Ref]


Ocular side effects have included blurring of vision and visual disturbances.[Ref]


1. "Product Information. Endal CD (codeine / diphenhydramine / phenylephrine)." Tiber Laboratories, Suwanee, GA.

Some side effects of Endal CD (old formulation) may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about Endal CD (old formulation) (codeine / diphenhydramine / phenylephrine)

Professional resources

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