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Elestat Side Effects

Generic name: epinastine ophthalmic

Medically reviewed by Last updated on Nov 25, 2020.

Note: This document contains side effect information about epinastine ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Elestat.

For the Consumer

Applies to epinastine ophthalmic: ophthalmic solution

Side effects requiring immediate medical attention

Along with its needed effects, epinastine ophthalmic (the active ingredient contained in Elestat) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking epinastine ophthalmic:

More common

  • Burning sensation in the eye
  • increase in blood flow to the whites of the eyes
  • redness, itching, pain, swelling, or other irritation of the eye

Side effects not requiring immediate medical attention

Some side effects of epinastine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

- some side effects were similar to problem being treated

Less common

- some side effects were similar to problem being treated
  • Congestion
  • hoarseness
  • increased cough
  • pain or tenderness around the eyes and cheekbones
  • shortness of breath
  • stuffy nose
  • tender, swollen glands in the neck
  • tightness of the chest or wheezing
  • trouble with swallowing
  • troubled breathing
  • voice changes

For Healthcare Professionals

Applies to epinastine ophthalmic: ophthalmic solution


The most common ocular side effects reported were a burning sensation following instillation, folliculosis, hyperemia, and pruritus of the eye.[Ref]


Common: Burning, irritation, pruritus

Uncommon: Hyperemia, discharge, dryness, visual disturbance

Postmarketing reports: Increased lacrimation, eye pain[Ref]


Uncommon: Asthma, nasal irritation, rhinitis[Ref]

Nervous system

Uncommon: Headache, dysgeusia[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Elestat (epinastine ophthalmic)." Allergan Inc, Irvine, CA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.