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Elestat Side Effects

Generic Name: epinastine ophthalmic

Note: This page contains information about the side effects of epinastine ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Elestat.

For the Consumer

Applies to epinastine ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by epinastine ophthalmic (the active ingredient contained in Elestat). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking epinastine ophthalmic:

More common:
  • Burning sensation in the eye
  • increase in blood flow to the whites of the eyes
  • redness, itching, pain, swelling, or other irritation of the eye

Minor Side Effects

Some of the side effects that can occur with epinastine ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common: - some side effects were similar to problem being treated
  • Body aches or pain
  • chills
  • cough
  • difficulty with breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • nasal congestion
  • runny nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness
Less common: - some side effects were similar to problem being treated
  • Congestion
  • hoarseness
  • increased cough
  • pain or tenderness around the eyes and cheekbones
  • shortness of breath
  • stuffy nose
  • tender, swollen glands in the neck
  • tightness of the chest or wheezing
  • trouble with swallowing
  • troubled breathing
  • voice changes

For Healthcare Professionals

Applies to epinastine ophthalmic: ophthalmic solution


The most common ocular side effects reported were a burning sensation following instillation, folliculosis, hyperemia, and pruritus of the eye.[Ref]


Common: Burning, irritation, pruritus
Uncommon: Hyperemia, discharge, dryness, visual disturbance
Postmarketing reports: Increased lacrimation, eye pain[Ref]


Uncommon: Asthma, nasal irritation, rhinitis[Ref]

Nervous system

Uncommon: Headache, dysgeusia[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Elestat (epinastine ophthalmic)." Allergan Inc, Irvine, CA.

Not all side effects for Elestat may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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