DefenCath Side Effects
Generic name: heparin catheter lock solution / taurolidine catheter lock solution
Note: This document provides detailed information about DefenCath.
Applies to heparin catheter lock solution / taurolidine catheter lock solution: intraluminal solution Side Effects associated with heparin catheter lock solution / taurolidine catheter lock solution. Some dosage forms listed on this page may not apply specifically to the brand name DefenCath.
Applies to heparin catheter lock solution / taurolidine catheter lock solution: intraluminal solution.
General adverse events
The most common adverse effects occurring in 2% of patients or greater included hemodialysis catheter malfunction, hemorrhage/bleeding, nausea, vomiting, dizziness, musculoskeletal chest pain, and thrombocytopenia.[Ref]
Gastrointestinal
- Common (1% to 10%): Nausea/procedural nausea, vomiting/procedural vomiting
Hematologic
- Common (1% to 10%): Hemorrhage/bleeding, thrombocytopenia
- Uncommon (0.1% to 1%): Heparin-induced thrombocytopenia
Hemorrhage/bleeding includes hematoma/hemorrhage, intracranial hemorrhage, arteriovenous graft or fistula site hemorrhage, catheter site hematoma/hemorrhage, cerebral/cerebellar hemorrhage, eye/conjunctival hemorrhage, gastrointestinal hemorrhage, hematuria, hemobilia, hemoptysis, renal hematoma, and vaginal/uterine hemorrhage.
Hypersensitivity
- Uncommon (0.1% to 1%): Drug hypersensitivity
Metabolic
- Frequency not reported: Hypocalcemia
Musculoskeletal
- Common (1% to 10%): Musculoskeletal (non-cardiac) chest pain or discomfort
Nervous system
- Common (1% to 10%): Dizziness
- Frequency not reported: Dysgeusia
- Postmarketing reports: Paresthesia
Other
- Very common (10% or more): Hemodialysis catheter/device malfunction (17%), use of thrombolytic agent (16%), catheter removal (12%)
- Common (1% to 10%): Catheter removal without thrombolytic agent use
See also:
References
1. (2024) "Product Information. Defencath (heparin-taurolidine catheter lock solution)." CorMedix
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Further information
DefenCath side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.