DefenCath Side Effects

Generic name: heparin / taurolidine catheter lock solution

Note: This document provides detailed information about DefenCath.

Applies to heparin/taurolidine catheter lock solution: intraluminal solution Side Effects associated with heparin / taurolidine catheter lock solution. Some dosage forms listed on this page may not apply specifically to the brand name DefenCath.

Applies to heparin/taurolidine catheter lock solution: intraluminal solution.

General adverse events

The most common adverse effects occurring in 2% of patients or greater included hemodialysis catheter malfunction, hemorrhage/bleeding, nausea, vomiting, dizziness, musculoskeletal chest pain, and thrombocytopenia.^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea/procedural nausea, vomiting/procedural vomiting

Hematologic

• Common (1% to 10%): Hemorrhage/bleeding, thrombocytopenia
• Uncommon (0.1% to 1%): Heparin-induced thrombocytopenia

Hemorrhage/bleeding includes hematoma/hemorrhage, intracranial hemorrhage, arteriovenous graft or fistula site hemorrhage, catheter site hematoma/hemorrhage, cerebral/cerebellar hemorrhage, eye/conjunctival hemorrhage, gastrointestinal hemorrhage, hematuria, hemobilia, hemoptysis, renal hematoma, and vaginal/uterine hemorrhage.

Hypersensitivity

• Uncommon (0.1% to 1%): Drug hypersensitivity

Metabolic

• Frequency not reported: Hypocalcemia

Musculoskeletal

• Common (1% to 10%): Musculoskeletal (non-cardiac) chest pain or discomfort

Nervous system

• Common (1% to 10%): Dizziness
• Frequency not reported: Dysgeusia
• Postmarketing reports: Paresthesia

Other

• Very common (10% or more): Hemodialysis catheter/device malfunction (17%), use of thrombolytic agent (16%), catheter removal (12%)
• Common (1% to 10%): Catheter removal without thrombolytic agent use

See also:

Further information

DefenCath side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer