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Decavac (Td) Side Effects

Generic Name: diphtheria toxoid / tetanus toxoid

Note: This page contains information about the side effects of diphtheria toxoid / tetanus toxoid. Some of the dosage forms included on this document may not apply to the brand name Decavac (Td).

For the Consumer

Applies to diphtheria toxoid / tetanus toxoid: intramuscular suspension

In addition to its needed effects, some unwanted effects may be caused by diphtheria toxoid / tetanus toxoid. In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking diphtheria toxoid / tetanus toxoid, check with your doctor or nurse immediately:

Less common:
  • Fever
  • general feeling of discomfort or illness
  • unusual tiredness or weakness
Incidence not known:
  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chills
  • convulsions
  • cough
  • difficulty with swallowing
  • dizziness
  • fainting
  • fast heartbeat
  • hives
  • itching
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid weight gain
  • shortness of breath
  • skin rash
  • swelling or puffiness of the face
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • tightness in the chest
  • tingling of the hands or feet
  • unusual weight gain or loss
  • wheezing

Minor Side Effects

Some of the side effects that can occur with diphtheria toxoid / tetanus toxoid may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Hard lumps, redness, tenderness, or warmth at the injection site
Less common:
  • Headache
Incidence not known:
  • Difficulty with moving
  • joint pain
  • lack or loss of strength
  • muscle aching or cramping
  • muscle stiffness
  • nausea
  • pain in the arms or legs
  • swollen joints
  • vomiting

For Healthcare Professionals

Applies to diphtheria toxoid / tetanus toxoid: intramuscular suspension


Local side effects have included erythema, tenderness, induration, swelling, redness, warmth, cellulitis, and nodules at the injection site.[Ref]


Hypersensitivity side effects have included allergic reactions (such as rash, urticaria, pruritus, and face edema) and anaphylactoid reactions.[Ref]


General side effects have included malaise and temperature elevations, pyrexia, chills, pain, asthenia, fatigue, and peripheral edema.[Ref]

Nervous system

Nervous system side effects have included headache, paresthesia, dizziness, syncope, and convulsions.[Ref]


Gastrointestinal side effects have included nausea and vomiting.[Ref]


Musculoskeletal side effects have included myalgia, arthralgia, pain in extremities, and musculoskeletal stiffness.[Ref]


1. "Product Information. Decavac (tetanus-diphtheria toxoids)." Aventis Pasteur Inc, Swiftwater, PA.

Not all side effects for Decavac (Td) may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.