Daranide Side Effects

Generic name: dichlorphenamide

Medically reviewed by Drugs.com. Last updated on Oct 11, 2024.

Note: This document provides detailed information about Daranide Side Effects associated with dichlorphenamide. Some dosage forms listed on this page may not apply specifically to the brand name Daranide.

Applies to dichlorphenamide: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to decide if you should continue to take it. Blood tests may be needed to check for unwanted effects.

Do not use this medicine together with high-dose aspirin. Using these medicines together may cause unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Check with your doctor right away if you have blistering, peeling, or red skin rash, fever with or without chills, itching skin, lower back or side pain, painful or difficult urination, sore throat, sores, ulcers, or white spots on the lips or in the mouth, unusual bleeding or bruising, or yellow eyes or skin.

Check with your doctor if you have convulsions, dry mouth, increased thirst, muscle pain or cramps, nausea or vomiting, numbness or tingling in the hands, feet, or lips, or uneven heartbeat. These may be symptoms of hypokalemia.

This medicine may cause metabolic acidosis. Tell your doctor right away if you have fast breathing, tiredness, loss of appetite, or irregular heartbeat while taking this medicine.

This medicine may cause some people to feel drowsy or more tired than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Common side effects of Daranide

Some side effects of dichlorphenamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• change in taste
• difficulty with moving
• general feeling of discomfort or illness
• loss of taste
• muscle pain or stiffness
• muscle spasms
• muscle twitching
• pain in the joints
• trouble performing routine tasks
• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Incidence not known

• decreased awareness or responsiveness
• loss of memory
• problems with memory
• seeing, hearing, or feeling things that are not there
• severe sleepiness

Serious side effects of Daranide

Along with its needed effects, dichlorphenamide (the active ingredient contained in Daranide) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dichlorphenamide:

Incidence not known

• abdominal or stomach pain
• black, tarry stools
• blistering, peeling, or loosening of the skin
• chest pain or discomfort
• chills
• confusion
• convulsions
• cough or hoarseness
• dark urine
• decreased urine
• diarrhea
• dilated neck veins
• dizziness
• drowsiness
• dry mouth
• extreme fatigue
• fever with or without chills
• general feeling of tiredness or weakness
• headache
• increased thirst
• irregular breathing
• irregular heartbeat
• itching or rash
• joint or muscle pain
• light-colored stools
• loss of appetite
• lower back or side pain
• mood changes
• muscle pain or cramps
• nausea or vomiting
• numbness or tingling in the hands, feet, or lips
• painful or difficult urination
• rapid, deep breathing
• red skin lesions, often with a purple center
• red, irritated eyes
• restlessness
• sore throat
• sores, ulcers, or white spots in the mouth or on the lips
• stomach cramps
• swelling of the face, fingers, feet, or lower legs
• swollen or painful glands
• tightness in the chest
• unpleasant breath odor
• unusual bleeding or bruising
• unusual tiredness or weakness
• vomiting of blood
• weight gain
• yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking dichlorphenamide:

Symptoms of overdose

• bloody or cloudy urine
• bloody, black, or tarry stools
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• continuing ringing or buzzing or other unexplained noise in the ears
• difficult or painful urination
• fainting
• hearing loss
• high fever
• pale skin
• shakiness and unsteady walk
• shakiness in the legs, arms, hands, or feet
• sudden decrease in the amount of urine
• unsteadiness, trembling, or other problems with muscle control or coordination

For healthcare professionals

Applies to dichlorphenamide: oral tablet.

Cardiovascular adverse events

• Postmarketing reports: Cardiac failure^[Ref]

Dermatologic

• Common (1% to 10%): Rash, pruritus^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, nausea^[Ref]

Hematologic

• Postmarketing reports: Pancytopenia^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity, anaphylaxis, idiosyncratic reactions^[Ref]

Metabolic

• Common (1% to 10%): Weight decreased
• Frequency not reported: Hypokalemia, metabolic acidosis^[Ref]

Musculoskeletal

• Common (1% to 10%): Muscle spasms, arthralgia, muscle twitching^[Ref]

Nervous system

• Very common (10% or more): Paresthesia (up to 44%), dysgeusia (up to 14%)
• Common (1% to 10%): Headache, hypoesthesia, lethargy, dizziness
• Postmarketing reports: Convulsion, syncope, tremor^[Ref]

Other

• Frequency not reported: Falls
• Postmarketing reports: Fetal death^[Ref]

Psychiatric

• Very common (10% or more): Cognitive disorder (up to 14%), confusional state (up to 11%)
• Postmarketing reports: Amnesia, hallucination, stupor, psychotic disorder^[Ref]

Renal

• Postmarketing reports: Nephrolithiasis, renal tubular necrosis^[Ref]

Respiratory

• Common (1% to 10%): Dyspnea, pharyngolaryngeal pain^[Ref]

See also:

Further information

Daranide side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer