Cilgavimab / Tixagevimab Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 10, 2024.

Applies to cilgavimab / tixagevimab: intramuscular solution.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your medical caregivers right away if you have:

• throat irritation, swelling in your face or throat;

• dizziness, a light-headed feeling (like you might pass out);

• chest pain, wheezing, shortness of breath;

• fever, chills, sweating, nausea;

• fast or slow heartbeats, headache, pounding in your neck or ears;

• weakness, tiredness;

• a rash or itching; or

• muscle pain.

Call your doctor if you have:

• confusion;

• weakness; or

• fast or slow heartbeats.

Also call your doctor at once, and get tested for COVID-19, if you develop any symptoms of COVID-19:

• fever, chills;

• cough, shortness of breath;

• tiredness;

• muscle or body aches;

• headache;

• sore throat;

• altered sense of taste or smell;

• stuffy or runny nose; or

• nausea, vomiting, or diarrhea.

Common side effects may include:

• headache;

• tiredness; or

• cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to cilgavimab / tixagevimab: intramuscular solution.

Cardiovascular adverse events

• Uncommon (0.1% to 1%): Serious cardiovascular events (including myocardial infarction, cardiac failure), serious thromboembolic events
• Frequency not reported: Cardiac serious adverse events, acute myocardial infarction, cardiac failure leading to death, sudden cardiac death^[Ref]

All patients who experienced cardiac serious adverse events had cardiac risk factors and/or history of cardiovascular disease at baseline.^[Ref]

Hypersensitivity

• Uncommon (0.1% to 1%): Hypersensitivity (included rash, urticaria)^[Ref]

Local

• Common (1% to 10%): Injection site reaction (included injection site pain, injection site erythema, injection site pruritus, injection site reaction, injection site induration)
• Frequency not reported: Injection-related reaction^[Ref]

See also:

Further information

Cilgavimab/tixagevimab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer