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Cilgavimab / Tixagevimab Dosage

Applies to the following strengths: 150 mg/1.5 mL-150 mg/1.5 mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Pre-Exposure Prophylaxis

For investigational use only

Initial Dose:


Dosing for Patients Who Initially Received Cilgavimab 150 mg and Tixagevimab 150 mg:

Repeat Dosing:

Comments:

Use: For the preexposure prophylaxis of COVID-19 in patients who are not currently infected with SARS-CoV-2 and have not had a known recent exposure to someone infected with SARS-CoV-2 AND:

Usual Pediatric Dose for Pre-Exposure Prophylaxis

For investigational use only

12 years or older weighing at least 40 kg:
Initial Dose:


Dosing for Patients Who Initially Received Cilgavimab 150 mg and Tixagevimab 150 mg:

Repeat Dosing:

Comments:

Use: For the preexposure prophylaxis of COVID-19 in patients who are not currently infected with SARS-CoV-2 and have not had a known recent exposure to someone infected with SARS-CoV-2 AND:

Renal Dose Adjustments

Renal dysfunction: No adjustment recommended

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
Previous severe hypersensitivity reactions (including anaphylaxis) to either active component or to any of the ingredients

Safety and efficacy have not been established in patients younger than 18 years; this product is not authorized for use in pediatric patients weighing less than 40 kg or younger than 12 years.

Dialysis

Data not available

Other Comments

January 26, 2023: Due to the high frequency of circulating SARS-CoV-2 variants that are nonsusceptible to this product, cilgavimab co-packaged with tixagevimab is not currently authorized in any US region; therefore, this product may not be administered for preexposure prophylaxis for prevention of COVID-19 under the EUA until further notice by the US FDA.

Administration advice:


Storage requirements:

Reconstitution/preparation techniques:

General:

Patient advice:

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.