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Bepotastine ophthalmic Side Effects

Medically reviewed by Last updated on Mar 29, 2022.

For the Consumer

Applies to bepotastine ophthalmic: ophthalmic solution

Side effects requiring immediate medical attention

Along with its needed effects, bepotastine ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking bepotastine ophthalmic:

Less common

  • Red, sore eyes

Incidence not known

  • Body rash
  • itching
  • swelling of the lips, tongue, or throat

Side effects not requiring immediate medical attention

Some side effects of bepotastine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Mild taste in your mouth

Less common

For Healthcare Professionals

Applies to bepotastine ophthalmic: ophthalmic solution


The most common side effect reported was a mild taste following instillation.


Common (1% to 10%): Eye irritation[Ref]

Nervous system

Very common (10% or more): Taste abnormality (25%)

Common (1% to 10%): Headache[Ref]


Common (1% to 10%): Nasopharyngitis[Ref]


Postmarketing reports: Itching, body rash, swelling of lips, tongue and/or throat


1. "Product Information. Bepreve (bepotastine ophthalmic)." ISTA Pharmaceuticals (2009):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.