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BayGam Side Effects

Generic Name: immune globulin intramuscular

Note: This document contains side effect information about immune globulin intramuscular. Some of the dosage forms listed on this page may not apply to the brand name BayGam.

For the Consumer

Applies to immune globulin intramuscular: intramuscular injectable

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Irritation where this drug is given.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to immune globulin intramuscular: intramuscular solution

Local

Local injection site pain and tenderness have occurred.[Ref]

Hypersensitivity

Hypersensitivity reactions have been rare, however, anaphylaxis has been reported. The mechanism has not been clearly established. Activation of the complement system by immune globulin aggregates present in the preparations has been suggested.[Ref]

Immunologic

All U.S. immune globulin products undergo viral inactivation and/or removal. No method has been totally effective in removing all risk and the potential exists for the presence of unknown infectious agents.[Ref]

References

1. Gardulf A, Hammarstrom L, Smith CI "Home treatment of hypogammaglobulinaemia with subcutaneous gammaglobulin by rapid infusion." Lancet 338 (1991): 162-6

2. "Product Information. BayGam (immune globulin intramuscular)" Bayer, West Haven, CT.

3. Kamme C, Coster C, Hagelquist E, Kalen N, Lindholm H, Grubb R "Side effects of treatment of hypogammaglobulinaemia with gammaglobulin." Acta Med Scand 179 (1966): 679-90

4. Kleinman PK, Weksler ME "Repeated reactions following intramuscular injection of gamma globulin." J Pediatr 83 (1973): 827-9

5. Pollack S, Cunningham-Rundles C, Good RA, Day NK "C1 esterase inhibitor deficiency in X-linked hypogammaglobulinaemia: an anomaly fostering anaphylactoid reactions following intramuscula gammaglobulin administration." Postgrad Med J 62 (1986): 939-42

6. Soothill JF "Hypogammaglobulinaemia in the United Kingdom. XI. Reactions to immunoglobulin." Med Res Counc Spec Rep Ser (Lond) 310 (1971): 106-14

7. Shemin ER "Anaphylactic reaction to gamma-globulin." JAMA 203 (1968): 59

8. Frankel SJ, Polmar SH, Grumet FC, Wedner HJ "Anti-IgA antibody associated reactions to intravenous gammaglobulin in a patient who tolerated intramuscular gammaglobulin." Ann Allergy 56 (1986): 436-9

Some side effects of BayGam may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about BayGam (immune globulin intramuscular)

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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