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Immune Globulin Intramuscular Dosage

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Hepatitis A

Household or institutional hepatitis A case contacts:
0.02 mL/kg

Persons who plan to travel to areas where hepatitis A is common.
Length of stay;
< 3 months: 0.02 mL/kg
3 months or longer: 0.06 mL/kg (repeat every 4 to 6 months)

Usual Adult Dose for Measles

Susceptible persons exposed < 6 days previously:
0.2 mL/kg. Maximum dose: 15 mL.

Usual Adult Dose for Rubella

Some studies suggest that the use of immune globulin intramuscular in exposed, susceptible women can lessen the likelihood of infection and fetal damage; therefore, immune globulin intramuscular at a dose of 0.55 mL/kg may benefit those women who will not consider a therapeutic abortion.

Usual Adult Dose for Varicella-Zoster

If varicella zoster immune globulin is not available, immune globulin intramuscular at a dose of 0.6 to 1.2 mL/kg, promptly given, may also modify varicella.

Usual Pediatric Dose for Hepatitis A

The safety and efficacy of immune globulin intramuscular have not been established in pediatric patients. However, immune globulin intramuscular may be appropriate for use in some situations.

Household or institutional hepatitis A case contacts:
0.02 mL/kg

Persons who plan to travel to areas where hepatitis A is common.
Length of stay;
< 3 months: 0.02 mL/kg
3 months or longer: 0.06 mL/kg (repeat every 4 to 6 months)

Usual Pediatric Dose for Measles

The safety and efficacy of immune globulin intramuscular have not been established in pediatric patients. However, immune globulin intramuscular may be appropriate for use in some situations.

Susceptible persons exposed < 6 days previously:
0.2 mL/kg. Maximum dose: 15 mL.

Susceptible and immunocompromised child: 0.5 mL/kg. Maximum dose: 15 mL.

Usual Pediatric Dose for Varicella-Zoster

The safety and efficacy of immune globulin intramuscular have not been established in pediatric patients. However, immune globulin intramuscular may be appropriate for use in some situations.

If varicella zoster immune globulin is not available, immune globulin intramuscular given at a dose of 0.6 to 1.2 mL/kg, promptly given, may also modify varicella.

Precautions

Do not administer IV.

In most people the intradermal injection of concentrated gamma globulin solution with its buffers causes a localized area of inflammation which can be misinterpreted as a positive allergic reaction. In actuality, this does not represent an allergic reaction. It is a localized tissue irritation of a chemical nature. Skin tests should not be done.

Immune globulin intramuscular is made from human plasma and may contain infectious agents, such as viruses, that can cause disease.

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