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Atrovent Nasal Side Effects

Generic Name: ipratropium nasal

Note: This document contains side effect information about ipratropium nasal. Some of the dosage forms listed on this page may not apply to the brand name Atrovent Nasal.

For the Consumer

Applies to ipratropium nasal: nasal spray

Along with its needed effects, ipratropium nasal (the active ingredient contained in Atrovent Nasal) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ipratropium nasal:

For the 0.03% nasal spray

More Common

Less Common

  • Blurred vision
  • burning, dry, or itching eyes
  • discharge or excessive tearing
  • itching, redness, tearing, or other sign of eye irritation not present before use of this medicine or becoming worse during use
  • nasal dryness
  • nosebleeds
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

Rare

  • Pain or cramping in the abdomen or stomach
  • painful or difficult urination

Incidence Not Known

  • Difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives or welts
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • skin rash
  • tightness in the chest

For the 0.06% nasal spray used for 4 days

Less Common

  • Nasal dryness
  • nosebleeds

Rare

  • Blurred vision
  • dizziness
  • eye redness or pain
  • fast, slow, or irregular heartbeat
  • pain or cramping in the abdomen or stomach
  • painful or difficult urination
  • ringing or buzzing in the ears
  • sore throat

Some side effects of ipratropium nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For the 0.03% nasal spray

Less common or rare

  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • dry mouth or throat
  • increased nasal congestion or runny nose
  • nasal itching, burning, or irritation
  • nausea

For the 0.06% nasal spray

Less common or rare

  • Dry mouth or throat
  • increased nasal congestion

For Healthcare Professionals

Applies to ipratropium nasal: nasal spray

General

The most frequently reported side effects were nasal dryness, epistaxis, headache, nasal discomfort, and throat irritation.[Ref]

Additional side effects have been reported from published literature and/or postmarketing surveillance when this drug was used alone or in combination with albuterol, including: urinary retention, prostatic disorders, mydriasis, cases of precipitation or worsening of narrow-angle glaucoma, acute eye pain, ocular irritation, wheezing, dryness of the oropharynx, tachycardia, edema, gastrointestinal distress (diarrhea, nausea, vomiting), bowel obstruction, constipation, nasal discomfort, throat irritation, hypersensitivity, accommodation disorder, intraocular pressure increased, glaucoma, halo vision, conjunctival hyperemia, corneal edema, heart rate increased, bronchospasm, pharyngeal edema, gastrointestinal motility disorder, mouth edema, stomatitis, and pruritus. After oral inhalation in patients suffering from chronic obstructive pulmonary disease (COPD)/asthma, supraventricular tachycardia and atrial fibrillation have been reported.[Ref]

Respiratory

Common (1% to 10%): Upper respiratory tract infection, epistaxis, nasal dryness, nasal irritation, nasal congestion, rhinorrhea increased, rhinitis increased, posterior nasal drip, sneezing, nasal polyps, nasal edema, pharyngitis, sinusitis, nasal discomfort, ulcerative rhinitis

Uncommon (0.1% to 1%): Bronchospasm, laryngospasm, pharyngeal edema

Frequency not reported: Hoarseness, cough, nasal burning[Ref]

Ocular

Uncommon (0.1% to 1%): Vision blurred, mydriasis, intraocular pressure increased, glaucoma, eye pain, halo vision, conjunctival hyperemia, corneal edema, accommodation disorder

Frequency not reported: Ocular irritation, conjunctivitis[Ref]

Local

Frequency not reported: Irritation[Ref]

Nervous system

Common (1% to 10%): Headache, taste perversion

Uncommon (0.1% to 1%): Dizziness[Ref]

Genitourinary

Uncommon (0.1% to 1%): Urinary retention[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Supraventricular tachycardia, atrial fibrillation, heart rate increased

Rare (less than 0.1%): Palpitation

Frequency not reported: Tachycardia[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, dry mouth/throat, diarrhea, throat irritation

Uncommon (0.1% to 1%): Gastrointestinal motility disorder, stomatitis

Frequency not reported: Dry mouth/throat[Ref]

Dermatologic

Uncommon (0.1% to 1%): Angioedema of throat/tongue/lips/face, rash

Rare (less than 0.1%): Urticaria, pruritus[Ref]

Immunologic

Uncommon (0.1% to 1%): Hypersensitivity, anaphylactic reaction[Ref]

Other

Common (1% to 10%): Pain

Frequency not reported: Thirst, tinnitus[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Ipratropium Bromide Nasal (ipratropium nasal)." West-Ward Pharmaceuticals Corporation (previously Roxane Laboratories Inc), Columbus, OH.

3. "Product Information. Atrovent nasal spray (ipratropium nasal)." Boehringer-Ingelheim, Ridgefield, CT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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