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Atgam Side Effects

Generic Name: lymphocyte immune globulin, anti-thy (equine)

Note: This page contains information about the side effects of lymphocyte immune globulin, anti-thy (equine). Some of the dosage forms included on this document may not apply to the brand name Atgam.

For the Consumer

Applies to lymphocyte immune globulin, anti-thy (equine): intravenous solution

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; chest pain, back pain; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • fast heartbeat, trouble breathing;

  • a light-headed feeling, like you might pass out;

  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin, coughing up blood or vomit that looks like coffee grounds;

  • seizure (convulsions); or

  • low white blood cell counts--fever, swollen glands, skin sores, rash or itching, muscle or joint pain, feeling very weak or tired.

Common side effects may include:

  • fever, chills, night sweats, or other signs of infection;

  • blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;

  • nausea, vomiting, diarrhea;

  • pain where the medicine was injected;

  • red or itching skin;

  • abnormal liver or kidney function tests;

  • dizziness, headache, confusion; or

  • redness, swelling, warmth, irritation, or tenderness in the veins of your arms or legs.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to lymphocyte immune globulin, anti-thy (equine): intravenous solution

General

General side effects have included fever, chills, herpes simplex reactivation, localized infection, systemic infection, possible serum sickness, lymphadenopathy, post-cervical lymphadenopathy, tender lymph nodes and night sweats.[Ref]

Hypersensitivity

Hypersensitivity side effects have included anaphylaxis.[Ref]

Dermatologic

Dermatologic side effects have included rash, pruritus, urticaria, wheal, flare, toxic epidermal necrosis and wound dehiscence.[Ref]

Musculoskeletal

Musculoskeletal side effects have included arthralgia, chest, flank or back pain, leg pains, myalgia, joint stiffness, muscle ache, burning soles, burning palms, and foot sole pain.[Ref]

Gastrointestinal

Gastrointestinal side effects have included GI bleeding or perforation, hiccoughs, epigastric pain, stomach pain, diarrhea, abdominal pain, stomatitis, laryngospasm, nausea and vomiting.[Ref]

Cardiovascular

Cardiovascular side effects have included hypertension, hypotension, tachycardia, congestive heart failure, edema, vasculitis and deep vein thrombosis, thrombophlebitis, clotted A-V fistula, myocarditis, cardiac irregularity, bradycardia, renal artery thrombosis, and iliac vein obstruction.[Ref]

Hematologic

Hematologic side effects have included thrombocytopenia, leukopenia, hepatosplenomegaly, neutropenia or granulocytopenia, anemia and thrombophlebitis.[Ref]

Respiratory

Respiratory side effects have included respiratory distress, dyspnea, apnea, pulmonary edema, bilateral pleural effusion, laryngospasm/edema, cough and sore mouth/throat.[Ref]

Nervous system

Nervous system side effects have included headache, dizziness, paresthesia, weakness or faintness, agitation/lethargy, listlessness, lightheadedness, seizures, malaise, confusion or disorientation, abnormal involuntary movement or tremor, possible encephalitis or post viral encephalopathy and rigidity.[Ref]

Local

Local side effects have included pain at the infusion site.[Ref]

Renal

Renal side effects have included proteinuria.[Ref]

Ocular

Ocular side effects have included periorbital edema.[Ref]

Metabolic

Metabolic side effects have included hyperglycemia.[Ref]

Hepatic

Hepatic side effects have included hepatosplenomegaly.[Ref]

References

1. "Product Information. Atgam (lymphocyte immune globulin, anti-thy (equine))." Pfizer U.S. Pharmaceuticals Group, New York, NY.

Not all side effects for Atgam may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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