Skip to main content

Aspirin / Hydrocodone Side Effects

Applies to aspirin / hydrocodone: oral tablet.

Important warnings This medicine can cause some serious health issues

You should not use this medication if you are allergic to aspirin or hydrocodone, or if you have a recent history of stomach or intestinal bleeding, a bleeding disorder such as hemophilia, or an allergy to an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.

Before you take aspirin and hydrocodone, tell your doctor about all of your medical conditions, especially if you have heart disease, high blood pressure, liver or kidney disease, a stomach or intestinal disorder, breathing problems, urination problems, seizures or a head injury, or a history of mental illness or drug/alcohol addiction.

Do not use any other over-the-counter medication without first asking your doctor or pharmacist.

Aspirin is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much aspirin.

There are many other medicines that can interact with aspirin and hydrocodone Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Avoid taking acetaminophen (Tylenol) or an NSAID (non-steroidal anti-inflammatory drug) while you are taking aspirin and hydrocodone, unless your doctor tells you to.

Hydrocodone may be habit-forming and should be used only by the person this medicine was prescribed for. Keep the medication in a secure place where others cannot get to it.

Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox.

Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children.

Do not take aspirin and hydrocodone during pregnancy unless your doctor has told you to.

Get emergency medical help if you have any of these signs of an allergic reaction while taking aspirin / hydrocodone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

Less serious side effects of aspirin / hydrocodone may include:

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Further information

Aspirin/hydrocodone side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer