Antivenin Polyvalent Side Effects
Generic Name: antivenin (crotalidae) polyvalent
Note: This document contains side effect information about antivenin (crotalidae) polyvalent. Some of the dosage forms listed on this page may not apply to the brand name Antivenin Polyvalent.
For the Consumer
Applies to antivenin (crotalidae) polyvalent: injection kit
Other dosage forms:
Along with its needed effects, antivenin (crotalidae) polyvalent (the active ingredient contained in Antivenin Polyvalent) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking antivenin (crotalidae) polyvalent:
- Difficulty in breathing or swallowing
- itching, especially of feet or hands
- reddening of skin, especially around ears
- swelling of eyes, face, or inside of nose
- unusual tiredness or weakness (sudden and severe)
For up to 24 days after you have received pit viper antivenin, you may develop symptoms of a side effect called serum sickness. The severity of the symptoms and the length of the sickness depend on the amount of pit viper antivenin you were given and how long the treatment lasted. During the 24 days after treatment with pit viper antivenin, check with your doctor if you notice any of the following side effects:
- joint pain
- rash and itching
- swollen lymph glands
For Healthcare Professionals
Applies to antivenin (crotalidae) polyvalent: injectable solution, intravenous powder for injection
The most common adverse events were urticaria and rash.
Very common (10% or more): Urticaria (16%), rash (11%)
Allergic reaction consisted of urticaria, dyspnea, and wheezing. Serum sickness included urticaria, cough, rash, pruritus, and urticaria. Acute allergic reactions manifested as anxiety, bronchospasm, chills, edema, fever, hypotension, pruritus, rash, urticaria, voice alteration, and/or wheezing.[Ref]
Common (1% to 10%): Allergic reaction, serum sickness
Common (1% to 10%): Coagulation disorder
Common (1% to 10%): Hypotension
Postmarketing reports: Tachycardia
Common (1% to 10%): General paresthesia, nervousness
Postmarketing reports: Tremor, dizziness, headache[Ref]
Common (1% to 10%): Asthma, cough, increased sputum
Postmarketing reports: Tachypnea, bronchospasm, wheezing, tracheal edema, dyspnea
Common (1% to 10%): Back pain, myalgia
Postmarketing reports: Musculoskeletal chest pain, chills
Common (1% to 10%): Nausea, anorexia, circumoral paresthesia
Postmarketing reports: Tongue swelling, lip swelling
Common (1% to 10%): Chest pain, wound infection, chills
Postmarketing reports: Failure to achieve initial control, recurrent swelling refractory to treatment, prolonged hospitalization, treatment failure resulting in death, chest discomfort, swelling
Common (1% to 10%): Nervousness
Postmarketing reports: Worsening eye sight
1. "Product Information. Crofab (antivenin (crotalidae) polyvalent)" Savage Laboratories, Melville, NY.
Some side effects may not be reported. You may report them to the FDA.