Antivenin Polyvalent Side Effects
Generic name: antivenin (crotalidae) polyvalent
Medically reviewed by Drugs.com. Last updated on Oct 28, 2022.
Note: This document contains side effect information about antivenin (crotalidae) polyvalent. Some dosage forms listed on this page may not apply to the brand name Antivenin Polyvalent.
Applies to antivenin (crotalidae) polyvalent: intravenous powder for solution.
Serious side effects
Along with its needed effects, antivenin (crotalidae) polyvalent (the active ingredient contained in Antivenin Polyvalent) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking antivenin (crotalidae) polyvalent:
- difficulty in moving
- difficulty swallowing
- fast heartbeat
- feeling of discomfort
- hives, itching, skin rash
- joint pain or swelling
- large, flat, blue or purplish patches in the skin
- muscle cramps, pain, or stiffness
- problems with bleeding or clotting
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- swollen lymph glands
- tightness in the chest
- unusual tiredness or weakness
- Blurred vision
- chest pain or discomfort
- difficulty breathing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast, pounding, or irregular heartbeat or pulse
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- noisy breathing
- rapid, shallow breathing
Incidence not known
- Black, tarry stools
- bleeding gums
- blood in the urine or stools
- itching, swelling, redness, tenderness, or hard lump at the injection site
- pinpoint red spots on the skin
- unusual bleeding or bruising
Other side effects
Some side effects of antivenin (crotalidae) polyvalent may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Bone pain
- feeling cold
For Healthcare Professionals
Applies to antivenin (crotalidae) polyvalent: injectable solution, intravenous powder for injection.
The most common adverse events were urticaria and rash.
Very common (10% or more): Urticaria (16%), rash (11%)
Allergic reaction consisted of urticaria, dyspnea, and wheezing. Serum sickness included urticaria, cough, rash, pruritus, and urticaria. Acute allergic reactions manifested as anxiety, bronchospasm, chills, edema, fever, hypotension, pruritus, rash, urticaria, voice alteration, and/or wheezing.[Ref]
Common (1% to 10%): Allergic reaction, serum sickness
Common (1% to 10%): Coagulation disorder
Postmarketing reports: Delayed or recurrent coagulopathy or thrombocytopenia, thrombocytopenia refractory to treatment, bleeding
Common (1% to 10%): Hypotension
Postmarketing reports: Tachycardia
Common (1% to 10%): General paresthesia, nervousness
Postmarketing reports: Tremor, dizziness, headache[Ref]
Common (1% to 10%): Asthma, cough, increased sputum
Postmarketing reports: Tachypnea, bronchospasm, wheezing, tracheal edema, dyspnea
Common (1% to 10%): Back pain, myalgia
Postmarketing reports: Musculoskeletal chest pain, chills
Common (1% to 10%): Nausea, anorexia, circumoral paresthesia
Postmarketing reports: Tongue swelling, lip swelling
Common (1% to 10%): Chest pain, wound infection, chills
Postmarketing reports: Failure to achieve initial control, recurrent swelling refractory to treatment, prolonged hospitalization, treatment failure resulting in death, chest discomfort, swelling
Common (1% to 10%): Nervousness
Postmarketing reports: Worsening eye sight
More about Antivenin Polyvalent (antivenin (crotalidae) polyvalent)
Related treatment guides
1. "Product Information. CroFab (antivenin (Crotalidae) polyvalent)." Savage Laboratories
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.