Medically reviewed by Drugs.com. Last updated on Jun 27, 2020.
(sul KON a zole)
- Sulconazole Nitrate
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Cream, External, as nitrate:
Exelderm: 1% (15 g [DSC], 30 g [DSC], 60 g) [contains cetyl alcohol, propylene glycol]
Generic: 1% (60 g)
Solution, External, as nitrate:
Exelderm: 1% (30 mL) [contains propylene glycol]
Generic: 1% (30 mL)
Brand Names: U.S.
- Antifungal Agent, Imidazole Derivative
- Antifungal Agent, Topical
Substituted imidazole derivative which inhibits metabolic reactions necessary for the synthesis of ergosterol, an essential membrane component. The end result is usually fungistatic; however, sulconazole may act as a fungicide in Candida albicans and Candida parapsilosis during certain growth phases.
Topical: ~8.7% percutaneously (Franz 1988)
Use: Labeled Indications
Cream: Treatment of tinea pedis (athlete's foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis; treatment of tinea versicolor
Solution: Treatment of tinea cruris and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis; treatment of tinea versicolor
Limitations of use: Effectiveness has not been proven in tinea pedis (athlete's foot).
Hypersensitivity to sulconazole or any component of the formulation
Tinea corporis/tinea cruris/tinea versicolor: Topical: Apply a small amount to the affected and surrounding skin areas once or twice daily for 3 weeks.
Tinea pedis: Topical: Cream: Apply a small amount to the affected area twice daily for 4 weeks.
Dosage adjustment for concomitant therapy: Significant drug interactions exist, requiring dose/frequency adjustment or avoidance. Consult drug interactions database for more information.
Refer to adult dosing.
For external use only; avoid contact with the eyes. Apply a small amount and gently massage into affected and surrounding skin areas.
Avoid excessive heat, above 40°C (104°F); protect solution from light.
There are no known significant interactions.
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
1% to 10%:
Central nervous system: Localized burning
Dermatologic: Localized erythema, pruritus, stinging of the skin
Concerns related to adverse effects:
• Irritation: Discontinue if sensitivity or irritation occurs.
• Appropriate use: For topical use only; avoid contact with eyes.
Pregnancy Risk Factor
Adverse events have been observed in animal reproduction studies with large doses administered orally. Systemic absorption is limited following topical administration.
What is this drug used for?
• It is used to treat fungal infections of the skin.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
• Skin irritation
• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Note: This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.
Consumer Information Use and Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a limited summary of general information about the medicine's uses from the patient education leaflet and is not intended to be comprehensive. This limited summary does NOT include all information available about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not intended to provide medical advice, diagnosis or treatment and does not replace information you receive from the healthcare provider. For a more detailed summary of information about the risks and benefits of using this medicine, please speak with your healthcare provider and review the entire patient education leaflet.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about sulconazole topical
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- En Español
- Drug class: topical antifungals
Other brands: Exelderm