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Zyloprim

Generic Name: allopurinol (AL oh PURE i nol)
Brand Name: Zyloprim

Medically reviewed on Aug 28, 2018

What is Zyloprim?

Zyloprim reduces the production of uric acid in your body. Uric acid buildup can lead to gout or kidney stones.

Zyloprim is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment.

Zyloprim may also be used for purposes not listed in this medication guide.

Important Information

You should not use Zyloprim if you have ever had a serious allergic reaction to Zyloprim. Stop taking the medicine and call your doctor at once if you have any signs of skin rash, no matter how mild.

Before taking this medicine

You should not take Zyloprim if you are allergic to it.

Tell your doctor if you have ever had:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I take Zyloprim?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take each dose with a full glass of water. To reduce your risk of kidney stones forming, drink 8 to 10 full glasses of fluid every day, unless your doctor tells you otherwise.

Take with food if Zyloprim upsets your stomach.

You may have gout attacks more often when you first start taking Zyloprim. Your doctor may recommend other gout medication to take with this medicine. Keep using your medication as directed and tell your doctor if your symptoms do not improve after 6 weeks of treatment.

You may need to follow a special diet while using Zyloprim. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Zyloprim?

Avoid driving or hazardous activity until you know how Zyloprim will affect you. Your reactions could be impaired.

Avoid drinking alcohol. It may worsen your condition.

Zyloprim side effects

Stop using Zyloprim and call your doctor at once if you have:

  • the first sign of any skin rash, no matter how mild;

  • flu symptoms, joint pain, easy bruising, unusual bleeding;

  • painful urination, blood in the urine;

  • little or no urination;

  • numbness, tingling, burning pain;

  • worsening gout symptoms; or

  • liver problems--loss of appetite, weight loss, stomach pain (upper right side), itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Zyloprim?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect Zyloprim, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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