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Tepezza

Generic Name: teprotumumab (TEP roe TOOM ue mab)
Brand Name: Tepezza

Medically reviewed by Drugs.com on Feb 18, 2020. Written by Cerner Multum.

What is Tepezza?

Tepezza is used to treat thyroid eye disease (sometimes called Graves Eye Disease).

Thyroid eye disease is an autoimmune disorder in which the immune system attacks tissues around the eyes. Symptoms include dry or watery eyes, eye redness, bulging eyes, vision problems, and difficulty closing the eyes.

Tepezza may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

Tell your doctor if you have ever had:

Tepezza may harm an unborn baby. Use effective birth control to prevent pregnancy while you are receiving Tepezza and for at least 6 months after your last dose. Tell your doctor if you become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

How is Tepezza given?

Tepezza is given as an infusion into a vein. A healthcare provider will give you this injection.

Tepezza is usually given once every 3 weeks for a total of 8 doses.

This medicine must be given slowly, and the infusion can take 60 to 90 minutes to complete.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Tepezza.

What happens if I overdose?

Since Tepezza is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving Tepezza?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Tepezza side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during an injection or within 1.5 hours afterward. Tell your caregiver if you feel hot, anxious, or short of breath, or if you have a headache, muscle pain, or fast heartbeats.

Call your doctor at once if you have:

  • diarrhea (with or without blood);

  • stomach cramps;

  • bowel movements that occur suddenly;

  • loss of bowel control;

  • a feeling of not completely emptying your bowels;

  • rectal bleeding; or

  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor.

Common side effects may include:

  • muscle spasms;

  • nausea, diarrhea;

  • headache, tiredness;

  • high blood sugar;

  • hair loss;

  • hearing problems;

  • dry skin; or

  • altered sense of taste.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tepezza?

Other drugs may affect Tepezza, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Frequently asked questions

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.