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Povidone iodine ophthalmic

Generic name: povidone iodine ophthalmic [ PO-vi-done-EYE-oh-dine ]
Brand name: Betadine Ophthalmic Solution
Dosage form: ophthalmic solution (5%)
Drug class: Ophthalmic anti-infectives

Medically reviewed by on Jun 2, 2023. Written by Cerner Multum.

What is povidone iodine ophthalmic?

Povidone iodine ophthalmic (for the eyes) is used to help prevent infection during surgery or other medical procedures performed on or around your eyes.

Povidone iodine ophthalmic may also be used for purposes not listed in this medication guide.

Povidone iodine ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects of povidone iodine ophthalmic may include:

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


A healthcare professional will apply this medicine while you are being prepared for eye surgery or medical procedure.

Before taking this medicine

You should not be treated with povidone iodine ophthalmic if you are allergic to iodine.

Tell your doctor if you have ever had a thyroid disorder.

Tell your doctor if you are pregnant or breastfeeding.

How is povidone iodine ophthalmic used?

Povidone iodine ophthalmic is applied to your eyelids, eyebrows, and the skin around your eyes. A healthcare professional will apply povidone iodine ophthalmic while you are being prepared for your surgery or medical procedure.

For a short time after surgery, this medicine may leave a slight yellow stain on the whites of your eyes or on the skin where this medicine was applied. Ask your healthcare provider if you have concerns about iodine staining in your eyes.

Povidone iodine stains can usually be removed from the skin with soap and water. Ask your healthcare provider for instructions about how to remove the stains.

What happens if I miss a dose?

Povidone iodine ophthalmic is used as a single dose in a clinical setting and does not have a daily dosing schedule.

What happens if I overdose?

Since povidone iodine ophthalmic is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving povidone iodine ophthalmic?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect povidone iodine ophthalmic?

Povidone iodine ophthalmic is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

More about povidone iodine ophthalmic

Patient resources

Other brands

Betadine Ophthalmic Solution

Professional resources

Other brands

Betadine Ophthalmic Solution

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.