What is Lodosyn?
Lodosyn and levodopa are also used to treat Parkinson-like symptoms caused by taking certain medicines or by exposure to poisonous gases or minerals such as carbon monoxide or manganese.
Lodosyn is only used in combination with levodopa and has no effect when used alone.
Lodosyn may also be used for purposes not listed in this medication guide.
Lodosyn side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
The following side effects may occur when Lodosyn is taken with levodopa.
Lodosyn may cause serious side effects. Call your doctor at once if you have:
uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
worsening of tremors (uncontrolled shaking);
confusion, hallucinations, unusual changes in mood or behavior;
depression or suicidal thoughts;
seizure (convulsions); or
Some people taking Lodosyn with levodopa have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking Lodosyn. Talk with your doctor if this occurs.
You may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.
Common side effects of Lodosyn may include:
nausea, upset stomach;
sleep problems (insomnia), dreaming more than usual;
dry mouth, burning feeling in your tongue;
weight changes; or
abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking this medicine
You should not use Lodosyn if you are allergic to it, or if you have:
Do not use Lodosyn if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
Tell your doctor if you have ever had:
nausea and vomiting while taking levodopa;
liver or kidney disease;
a stomach or intestinal ulcer;
depression, mental illness, or psychosis.
It is not known if Lodosyn will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
You should not breastfeed while using Lodosyn.
Not approved for use by anyone younger than 18 years old.
How should I take Lodosyn?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
If you already take levodopa but have never taken Lodosyn, start taking both medicines at least 12 hours after you last took levodopa by itself.
Take both Lodosyn and levodopa together at regular intervals, to keep steady amounts in your body at all times.
You may need frequent medical tests.
Your symptoms may not improve for several weeks. Call your doctor if your symptoms do not improve or if the effects of this medicine wear off quickly between doses.
You may have withdrawal symptoms if you stop using Lodosyn suddenly. Ask your doctor before stopping the medicine.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Lodosyn.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Get your prescription refilled before you run out of medicine completely.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Lodosyn?
Avoid driving or hazardous activity until you know how Lodosyn will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Avoid taking iron supplements or eating a diet high in protein. These things can make it harder for your body to digest and absorb Lodosyn and levodopa. Talk with your doctor or dietitian about the best foods to eat or avoid.
What other drugs will affect Lodosyn?
The short-acting (immediate-release) formulation of carbidopa/levodopa takes effect within about 20 to 50 minutes. The long-acting (extended-release) formulation starts to work closer to the 50-minute timeframe. Continue reading
The immediate-release (short-acting) form of carbidopa/levodopa is usually taken 3 or 4 times each day, while the extended-release (long-acting) form is typically taken 2 to 4 times each day. Continue reading
Carbidopa/levodopa is unlikely to cause high blood pressure (hypertension). It was reported in less than 1% of patients in clinical trials and is not considered a common adverse reaction related to the drug. Continue reading
More about Lodosyn (carbidopa)
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- Drug class: dopaminergic antiparkinsonism agents
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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