Generic Name: anidulafungin (ay NID ue la FUN gin)
Brand Name: Eraxis
What is anidulafungin?
Anidulafungin is an antifungal medication that fights infections caused by fungus.
Anidulafungin treats candida (yeast) infections in the blood, or in the stomach or esophagus.
Anidulafungin may also be used for purposes not listed in this medication guide.
What is the most important information I should know about anidulafungin?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my health care provider before using anidulafungin?
You should not use this medicine if you are allergic to anidulafungin, caspofungin (Cancidas), micafungin (Mycamine), or similar antifungal medicines.
To make sure you can safely use anidulafungin, tell your doctor if you have liver disease.
FDA pregnancy category C. It is not known whether anidulafungin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether anidulafungin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How is anidulafungin given?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Anidulafungin is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Anidulafungin is a powder medicine that must be mixed with a liquid (diluent) before using it. You will then need to dilute this mixture into a solution with another liquid in an IV bag. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Anidulafungin is sometimes given for up to 14 days after lab tests show that the infection has cleared. Use this medicine for the full prescribed length of time. Anidulafungin will not treat a viral infection such as the flu or a common cold.
Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
Store the dry powder medicine in a refrigerator. Do not freeze.
After you mix the powder and diluent, you may store this mixture at room temperature for up to 24 hours before further diluting it. The final diluted solution may be stored at room temperature for up to 48 hours.
You may also store the diluted solution in a freezer for at least 72 hours before using it.
Do not use anidulafungin diluted solution if it has changed colors or has particles in it. Call your pharmacist for new medication.
What happens if I miss a dose?
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using anidulafungin?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Anidulafungin side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, itchy, sweaty, or if you have chest tightness or trouble breathing.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out;
pain or burning when you urinate;
liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
low potassium--confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling; or
low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating.
Common side effects may include:
upset stomach, nausea, vomiting, diarrhea;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Anidulafungin dosing information
Usual Adult Dose for Esophageal Candidiasis:
Initial dose: 100 mg IV on Day 1
Maintenance dose: 50 mg IV once a day thereafter
Duration: Treatment should be given for a minimum of 14 days and for at least 7 days following resolution of symptoms. Treatment duration should be based on the patient's clinical response. If the patient is infected with HIV, suppressive antifungal therapy may be considered after a course of treatment to minimize the risk of relapse.
Usual Adult Dose for Candidemia:
Candidemia and other Candida infections (intraabdominal abscess and peritonitis):
Initial dose: 200 mg IV on Day 1
Maintenance dose: 100 mg IV once a day thereafter
Duration: Duration of treatment should be based on the patient's clinical response. In general, antifungal therapy should continue for at least 14 days after the last positive culture.
What other drugs will affect anidulafungin?
Other drugs may interact with anidulafungin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
More about anidulafungin
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
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Other brands: Eraxis
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about anidulafungin.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.01.
Last reviewed: November 26, 2014
Date modified: February 03, 2017