Skip to Content

Anidulafungin Dosage

Applies to the following strength(s): 50 mg ; 100 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Esophageal Candidiasis

Initial dose: 100 mg IV on Day 1
Maintenance dose: 50 mg IV once a day thereafter

Duration: Treatment should be given for a minimum of 14 days and for at least 7 days following resolution of symptoms. Treatment duration should be based on the patient's clinical response. If the patient is infected with HIV, suppressive antifungal therapy may be considered after a course of treatment to minimize the risk of relapse.

Usual Adult Dose for Candidemia

Candidemia and other Candida infections (intraabdominal abscess and peritonitis):
Initial dose: 200 mg IV on Day 1
Maintenance dose: 100 mg IV once a day thereafter

Duration: Duration of treatment should be based on the patient's clinical response. In general, antifungal therapy should continue for at least 14 days after the last positive culture.

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended.

Precautions

Clinically significant hepatic abnormalities have occurred in some patients with serious underlying medical conditions who were receiving multiple concomitant medications along with anidulafungin. Patients who develop abnormal liver function tests during anidulafungin therapy should be monitored for evidence of worsening hepatic function and evaluated for risk/benefit of continuing anidulafungin therapy.

Anaphylactic reactions (including shock) were reported with anidulafungin. If these reactions occur, anidulafungin should be discontinued and appropriate treatment administered.

Safety and effectiveness have not been established in pediatric patients 16 years of age or younger.

Dialysis

Anidulafungin is not dialyzable and may be administered without regard to the timing of hemodialysis.

Other Comments

The rate of infusion should not exceed 1.1 mg/minute.

Hide